Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | PRKACG | P22612 | 1/20 | 0.34 |
| ▸ | PRKACB | P22694 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 5/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20564864 | 0.79 | ALDH1A1 (0.37) | PRKACAPRKACGPRKACBIDO1NPSR1 | |
| SCHEMBL31278318 | 0.79 | PRKACA (0.46) | PRKACAPRKACGPRKACBMEN1KMT2A | |
| SCHEMBL21877758 | 0.69 | PRKACA (0.38) | PRKACAPRKACGPRKACBALDH1A1PKM | |
| SCHEMBL21877759 | 0.69 | PRKACA (0.38) | PRKACAPRKACGPRKACBALDH1A1PKM | |
| SCHEMBL17447896 | 0.68 | PIK3CD (0.45) | PRKACAPRKACGPRKACBMEN1KMT2A | |
| SCHEMBL17447898 | 0.68 | PIK3CD (0.45) | PRKACAPRKACGPRKACBMEN1KMT2A | |
| SCHEMBL15613582 | 0.68 | ADORA1 (0.54) | PRKACAPRKACGPRKACBIDO1MEN1 | |
| SCHEMBL31278050 | 0.67 | PRKACA (0.39) | PRKACAPRKACGPRKACB | |
| SCHEMBL23630311 | 0.65 | ALDH1A1 (0.43) | PRKACAPRKACGPRKACBMEN1KMT2A | |
| SCHEMBL17447903 | 0.64 | ADORA2A (0.36) | PRKACAPRKACGPRKACBADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591242-A | Compounds useful as kinase inhibitors | 洛克索肿瘤学股份有限公司 | 2022-06-07 | — | — | CN | disclosed |