SCHEMBL29711925

SCHEMBL29711925

Cc1ccc(S(=O)(=O)n2ccc3c(Cl)c(C#N)cnc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
BRD4 O60885 2/20 0.42
HSD11B1 P28845 1/20 0.40
PKM P14618 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
POLB P06746 1/20 0.37
ALDH3A1 P30838 1/20 0.37
HTT P42858 1/20 0.37
NOD1 Q9Y239 1/20 0.37
MAPT P10636 2/20 0.37
PTGS2 P35354 1/20 0.36
RAPGEF4 Q8WZA2 1/20 0.36
KDM1A O60341 3/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CCR6 P51684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28952200 1.00 L3MBTL1 (0.46) L3MBTL1BRD4HSD11B1PKMMEN1
SCHEMBL16042354 0.88 CYP2C19 (0.45) BRD4PKMMEN1KMT2AALDH1A1
SCHEMBL29713718 0.88 CYP2C19 (0.45) BRD4PKMMEN1KMT2AALDH1A1
SCHEMBL28072739 0.86 L3MBTL1 (0.46) L3MBTL1BRD4HSD11B1PKMMEN1
SCHEMBL30509477 0.84 L3MBTL1 (0.51) L3MBTL1BRD4HSD11B1PKMALDH1A1
SCHEMBL16052697 0.84 L3MBTL1 (0.51) L3MBTL1BRD4HSD11B1PKMALDH1A1
SCHEMBL1356064 0.84 L3MBTL1 (0.51) L3MBTL1BRD4HSD11B1PKMALDH1A1
SCHEMBL1749083 0.81 L3MBTL1 (0.55) L3MBTL1BRD4HSD11B1PKMMEN1
SCHEMBL20535940 0.81 L3MBTL1 (0.49) L3MBTL1BRD4PKMALDH1A1POLB
SCHEMBL1748728 0.81 L3MBTL1 (0.49) L3MBTL1BRD4PKMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114591321-A Aza-and-cyclic compounds, method for the production thereof and use thereof 广州费米子科技有限责任公司 2022-06-07 CN disclosed