Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ACAT2 | Q9BWD1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482967 | 0.84 | TAAR1 (0.48) | TAAR1ACHETSHRCTBP2CHRM2 | |
| SCHEMBL14616181 | 0.82 | TAAR1 (0.46) | TAAR1ACHETSHRCTBP2CHRM2 | |
| SCHEMBL15304790 | 0.82 | TAAR1 (0.46) | TAAR1ACHETSHRCTBP2CHRM2 | |
| SCHEMBL6582 | 0.79 | TAAR1 (0.43) | TAAR1ACHETSHRCTBP2CHRM2 | |
| SCHEMBL2564569 | 0.77 | MIF (0.52) | TAAR1ACHETSHRCTBP2CHRM2 | |
| SCHEMBL8244140 | 0.77 | TAAR1 (0.42) | TAAR1ACHETSHRCTBP2CHRM2 | |
| SCHEMBL2090458 | 0.77 | TAAR1 (0.56) | TAAR1ACHETSHRCHRM2PTGS1 | |
| SCHEMBL29477327 | 0.77 | TAAR1 (0.56) | TAAR1ACHETSHRCHRM2PTGS1 | |
| SCHEMBL143962 | 0.77 | TAAR1 (0.71) | TAAR1ACHETSHRCTBP2CHRM2 | |
| SCHEMBL40576 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700628-B2 | Aromatic ether derivatives useful as thrombin inhibitors | ELI LILLY AND COMPANY (US) | 2010-04-20 | — | — | US | claimed |
| EP-1817287-B1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | LILLY CO ELI (US) | 2010-02-10 | — | — | EP | claimed |
| US-20090227566-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2009-09-10 | — | — | US | claimed |
| EP-1817287-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | Eli Lilly and Company (US) | 2007-08-15 | — | — | EP | claimed |
| WO-2006057845-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | claimed |
| US-20240198316-A1 | SYNTHETIC POLYMERIC POROUS MEDIUM WITH HIERARCHICAL MULTIPLE LAYER STRUCTURE, ITS DESIGN, SYNTHESIS, MODIFICATION, AND LIQUID CHROMATOGRAPHIC APPLICATIONS | SUZHOU SEPAX TECHNOLOGIES, INC. (CN) | 2024-06-20 | — | — | US | disclosed |
| EP-1583567-B1 | Bacteria trapping wiping tissue | SCA HYGIENE PROD AB (SE) | 2012-03-14 | — | — | EP | disclosed |
| US-7947292-B2 | Bacteria trapping fibrous material | SCA HYGIENE PRODUCTS AB (SE) | 2011-05-24 | — | — | US | disclosed |
| US-20100278690-A1 | Bacteria trapping fibrous material | SCA HYGIENE PRODUCTS AB (SE) | 2010-11-04 | — | — | US | disclosed |
| US-7700628-B2 | Aromatic ether derivatives useful as thrombin inhibitors | ELI LILLY AND COMPANY (US) | 2010-04-20 | — | — | US | disclosed |
| EP-1817287-B1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | LILLY CO ELI (US) | 2010-02-10 | — | — | EP | disclosed |
| US-20090227566-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | ELI LILLY AND COMPANY | 2009-09-10 | — | — | US | disclosed |
| US-5889081-A | POLYCARBOSILANE | OSAKA GAS COMPANY LIMITED (JP) | 1999-03-30 | — | — | US | disclosed |
| EP-0882727-A1 | NOVEL PURINE DERIVATIVES | JAPAN ENERGY CORPORATION (JP) | 1998-12-09 | — | — | EP | disclosed |
| US-5233089-A | Charge transport material; used in electrophotographic plates to provide improved sensitivity, photoresponse and durability | HITACHI, LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0273426-A2 | Enamine derivatives, production thereof and electrophotographic plates containing the same | Hitachi Chemical Co., Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |
| US-4491663-A | TRIMERIZATION TO FORM ISOCYANURATE | FORD MOTOR COMPANY (US) | 1985-01-01 | — | — | US | disclosed |
| US-4486556-A | CORROSION RESISTANT, AUTOMOBILES AND APPLIANCES | FORD MOTOR COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| US-3998841-A | CHLOROTHIO-N-PHTHALIMIDE AND PROCESS THEREFOR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-12-21 | — | — | US | disclosed |
| US-3962527-A | Novel polymers and photographic elements containing same | EASTMAN KODAK COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227566-A1 | AROMATIC ETHER DERIVATIVES USEFUL AS THROMBIN INHIBITORS | TFPI, F2, F11 | TAAR1 2327/4885ACHE 1035/4885TSHR 975/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.