SCHEMBL6582

SCHEMBL6582

Cc1ccccc1CN=C=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.43
CTBP2 P56545 1/20 0.42
PTGS1 P23219 1/20 0.41
PTGS2 P35354 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
KMT2A Q03164 4/20 0.40
KEAP1 Q14145 1/20 0.39
NFE2L2 Q16236 1/20 0.39
HPGD P15428 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
ACHE P22303 1/20 0.38
CHRM2 P08172 1/20 0.37
MAPT P10636 2/20 0.37
MEN1 O00255 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 1/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127043 0.86 GABRA1 (0.41) TAAR1CTBP2GABRA1GABRB2HPGD
SCHEMBL29364508 0.86 GABRA1 (0.41) TAAR1CTBP2GABRA1GABRB2HPGD
Propane SCHEMBL28338597 0.84 GABRA1 (0.47) TAAR1CTBP2PTGS1PTGS2GABRA1
Benzene SCHEMBL28107745 0.84 GABRA1 (0.40) CTBP2GABRA1GABRB2KEAP1NFE2L2
SCHEMBL28225610 0.84 GABRA1 (0.40) GABRA1GABRB2HPGDALDH1A1
Water SCHEMBL5172983 0.84 GABRA1 (0.40) GABRA1GABRB2HPGDALDH1A1
SCHEMBL904507 0.83 GABRA1 (0.42) TAAR1CTBP2GABRA1GABRB2KEAP1
Trimethylammonium SCHEMBL28053835 0.83 GABRA1 (0.41) TAAR1GABRA1GABRB2ALDH1A1TSHR
SCHEMBL1457269 0.83 GABRA1 (0.50) GABRA1GABRB2KMT2ATSHRMAPT
SCHEMBL11253674 0.82 TAAR1 (0.48) TAAR1CTBP2PTGS1PTGS2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 579 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022059820-A1 PRODUCTION METHOD FOR ISOCYANATE COMPOUND COMPRISING NON-CHLORINATED DERIVATIVE, AND COMPOSITION OF SAME 케이에스랩(주) 2022-03-24 WO claimed
CN-113720925-A Separation detection method of isocyanate derivative 武汉武药科技有限公司 2021-11-30 CN claimed
US-20210171451-A1 DIISOCYANATE COMPOSITION, PREPARATION METHOD THEREOF AND OPTICAL MATERIAL USING SAME WOORI FINE CHEM CO., LTD. (KR) 2021-06-10 US claimed
EP-3831861-A1 DIISOCYANATE COMPOSITION, PREPARATION METHOD THEREOF AND OPTICAL MATERIAL USING SAME SKC Co., Ltd. (KR) 2021-06-09 EP claimed
CN-112920373-A Diisocyanate composition, method for preparing the same, and optical material using the same SKC株式会社 2021-06-08 CN claimed
CN-109725073-A The method for separating and detecting of acetylcysteine enantiomter 湖南华纳大药厂科技开发有限公司 2019-05-07 CN claimed
US-10092881-B2 Permanent hydrophilic porous coatings and methods of making them BHA ALTAIR, LLC (US) 2018-10-09 US claimed
US-20130338181-A1 TREATMENT OF EFFECT OF CHEMICALS WITH THEIR ULTRADILUTE STEREOISOMERS KUZEFF REINHARD MICHAEL (AU) 2013-12-19 US claimed
US-20090191399-A1 PERMANENT HYDROPHILIC POROUS COATINGS ONTO A SUBSTRATE AND POROUS MEMBRANES THEREOF GENERAL ELECTRIC COMPANY (US) 2009-07-30 US claimed
US-20090191398-A1 MEMBRANES COMPRISING HYDROPHILIC COATINGS GENERAL ELECTRIC COMPANY (US) 2009-07-30 US claimed
EP-1487448-A4 TREATMENT OF EFFECT OF CHEMICALS WITH THEIR ULTRADILUTE STEREOISOMERS SEMPACH PTY LTD (AU) 2007-04-25 EP claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
EP-1487448-A1 TREATMENT OF EFFECT OF CHEMICALS WITH THEIR ULTRADILUTE STEREOISOMERS Sempach PTY Ltd (AU) 2004-12-22 EP claimed
WO-2003072105-A1 TREATMENT OF EFFECT OF CHEMICALS WITH THEIR ULTRADILUTE STEREOISOMERS SEMPACH PTY LTD (AU) 2003-09-04 WO claimed
EP-0234353-A1 Process for the production of tetramethyl xylylene diisocyanates AMERICAN CYANAMID COMPANY (US) 1987-09-02 EP claimed
JP-54138544-A None JP disclosed
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
US-4242122-A CARBAMOYL-OXY AND -THIO DERIVATIVES OF PHENYLUREA MONSANTO COMPANY (US) 1980-12-30 US disclosed
JP-S54138544-A PREPARATION OF ALPHA-METHYLBENZYL ISOCYANATE OR ITS NUCLEAR SUBSTITUTION PRODUCT SHOWA DENKO KK 1979-10-27 JP disclosed
US-4013450-A Herbicidal ureido containing carbanilates MONSANTO COMPANY (US) 1977-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210171451-A1 DIISOCYANATE COMPOSITION, PREPARATION METHOD THEREOF AND OPTICAL MATERIAL USING SAME INCENP, IK, ALKBH5 TAAR1 3913/4885CTBP2 643/4885PTGS1 3821/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.