Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2967916 | 0.93 | CALM1 (0.45) | CALM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7315399 | 0.85 | CALM1 (0.56) | CALM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL7253321 | 0.85 | PDE4A (0.52) | CALM1KMT2AALDH1A1PDE4AMAPT | |
| SCHEMBL6035149 | 0.82 | MEN1 (0.56) | MEN1KMT2AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11823484 | 0.80 | PDE4A (0.42) | CALM1MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL12824881 | 0.79 | BIRC5 (0.45) | MEN1KMT2AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6895161 | 0.79 | ALDH1A1 (0.50) | MEN1KMT2AMAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4380153 | 0.79 | ALDH1A1 (0.49) | CALM1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6430844 | 0.76 | ALDH1A1 (0.48) | ALDH1A1HPGD | |
| SCHEMBL2704054 | 0.76 | TACR2 (0.47) | CALM1MEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7777060-B2 | Platinum analogs with bis-nitrile-containing ligands | BIONUMERIK PHARMACEUTICALS, INC. (US) | 2010-08-17 | — | — | US | claimed |