SCHEMBL29720404

SCHEMBL29720404

Cc1cc(C)c(O)c(C(C)C(C)c2cc(C)cc(C)c2O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
LMNA P02545 3/20 0.48
GAA P10253 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
CA2 P00918 3/20 0.40
CA1 P00915 2/20 0.40
SELL P14151 1/20 0.40
SELP P16109 1/20 0.40
SELE P16581 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.37
TP53 P04637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TRPA1 O75762 1/20 0.35
CHRM1 P11229 1/20 0.35
SLC6A2 P23975 1/20 0.35
ADRA1A P35348 1/20 0.35
HTR2B P41595 1/20 0.35
ACHE P22303 1/20 0.35
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536656 0.89 ALDH1A1 (0.43) ALDH1A1LMNAGAAKDM4EMAPT
SCHEMBL29612051 0.86 ALDH1A1 (0.48) ALDH1A1LMNAGAAKDM4EMAPT
SCHEMBL4402447 0.86 CA1 (0.52) ALDH1A1LMNAGAAKDM4EMAPT
SCHEMBL5612512 0.86 ALDH1A1 (0.48) ALDH1A1LMNAGAAKDM4EMAPT
SCHEMBL8571460 0.84 ALDH1A1 (0.46) ALDH1A1LMNAGAAKDM4EMAPT
SCHEMBL223172 0.82 ALDH1A1 (0.45) ALDH1A1LMNAGAAKDM4EMAPT
SCHEMBL29350282 0.82 ALDH1A1 (0.45) ALDH1A1LMNAGAAKDM4EMAPT
SCHEMBL9335579 0.79 ALDH1A1 (0.46) ALDH1A1LMNAGAAKDM4EMAPT
SCHEMBL5596195 0.79 ALDH1A1 (0.46) ALDH1A1LMNAGAAKDM4EMAPT
SCHEMBL14625525 0.79 ALDH1A1 (0.42) ALDH1A1LMNAGAAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114606012-A Polymerizable liquid crystal material and polymerized liquid crystal film 默克专利股份有限公司 2022-06-10 CN disclosed