SCHEMBL68664

SCHEMBL68664

Cc1cc(CCCCc2ccc(O)c(C)c2)ccc1O

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.68
ESR2 Q92731 2/20 0.68
IGF1R P08069 7/20 0.64
ALOX15 P16050 7/20 0.64
TP53 P04637 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CDK1 P06493 1/20 0.50
SLC28A3 Q9HAS3 1/20 0.48
KAT8 Q9H7Z6 2/20 0.47
SKP2 Q13309 1/20 0.47
AR P10275 1/20 0.47
NPC1 O15118 1/20 0.47
HPGD P15428 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
RAB9A P51151 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16065724 0.98 ESR1 (0.65) ESR1ESR2IGF1RALOX15TP53
SCHEMBL8402779 0.98 ESR1 (0.65) ESR1ESR2IGF1RALOX15TP53
SCHEMBL12949979 0.98 ESR1 (0.65) ESR1ESR2IGF1RALOX15TP53
SCHEMBL6227927 0.98 ESR1 (0.65) ESR1ESR2IGF1RALOX15TP53
SCHEMBL529618 0.95 ESR1 (0.68) ESR1ESR2IGF1RALOX15TP53
SCHEMBL26300971 0.94 ALOX15 (0.76) ESR1ESR2IGF1RALOX15TP53
SCHEMBL4557946 0.92 ESR1 (0.59) ESR1ESR2IGF1RALOX15TP53
SCHEMBL22500464 0.92 IGF1R (0.69) ESR1ESR2IGF1RALOX15TP53
SCHEMBL1924746 0.91 ESR1 (0.74) ESR1ESR2IGF1RALOX15TP53
SCHEMBL29720481 0.91 ESR1 (0.74) ESR1ESR2IGF1RALOX15TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
EP-0533722-A1 PHENOL RESIN, PROCESS FOR PRODUCING IT AND USE. HOECHST AG (DE) 1993-03-31 EP disclosed
WO-1991019749-A1 PHENOL RESIN, PROCESS FOR PRODUCING IT AND USE HOECHST AKTIENGESELLSCHAFT (DE) 1991-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 ESR1 1265/4885ESR2 2595/4885IGF1R 3321/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.