Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 2/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | USP5 | P45974 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPD | P32754 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29812432 | 0.87 | NOTUM (0.49) | L3MBTL1NOTUMKDM4ESMN1; SMN2POLB | |
| SCHEMBL29721079 | 0.83 | ALDH1A1 (0.41) | L3MBTL1NOTUMKDM4ESMN1; SMN2POLB | |
| SCHEMBL29720825 | 0.81 | KDM4E (0.50) | L3MBTL1NOTUMKDM4ESMN1; SMN2POLB | |
| SCHEMBL29812304 | 0.81 | NOTUM (0.49) | L3MBTL1NOTUMKDM4ESMN1; SMN2POLB | |
| SCHEMBL29720715 | 0.79 | HPGD (0.38) | L3MBTL1NOTUMKDM4ESMN1; SMN2POLB | |
| SCHEMBL28288439 | 0.78 | L3MBTL1 (0.50) | L3MBTL1NOTUMKDM4ESMN1; SMN2POLB | |
| SCHEMBL29812604 | 0.77 | NOTUM (0.48) | L3MBTL1NOTUMKDM4ESMN1; SMN2POLB | |
| SCHEMBL29812139 | 0.77 | NOTUM (0.45) | L3MBTL1NOTUMKDM4ESMN1; SMN2POLB | |
| SCHEMBL21776571 | 0.75 | NOTUM (0.46) | L3MBTL1NOTUMKDM4ESMN1; SMN2POLB | |
| SCHEMBL28881430 | 0.75 | NOTUM (0.46) | L3MBTL1NOTUMKDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110627796-B | Nitrogenous heterocyclic derivative and application thereof in medicine | 北京越之康泰生物医药科技有限公司 | 2022-07-12 | — | — | CN | disclosed |