Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.36 |
| ▸ | FURIN | P09958 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29721158 | 0.99 | MAPK8 (0.43) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL29496543 | 0.95 | MEN1 (0.44) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL8759336 | 0.91 | MEN1 (0.47) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL31487414 | 0.91 | MEN1 (0.47) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL17711236 | 0.91 | MEN1 (0.47) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL8759341 | 0.91 | MEN1 (0.47) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL31632216 | 0.90 | MEN1 (0.41) | MAPK8MAPK9MAPK10MEN1KMT2A | |
| SCHEMBL9120793 | 0.90 | GHSR (0.41) | MEN1KMT2APRCPGHSR | |
| SCHEMBL29588633 | 0.90 | GHSR (0.41) | MEN1KMT2APRCPGHSR | |
| SCHEMBL31385440 | 0.90 | GHSR (0.41) | MEN1KMT2APRCPGHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107266579-B | Fusion proteins for the treatment of metabolic diseases | 诺华股份有限公司 | 2022-07-12 | — | — | CN | disclosed |