SCHEMBL8759341

SCHEMBL8759341

N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ PRCP P42785 3/20 0.45
▸ DPP7 Q9UHL4 1/20 0.44
▸ CTSC P53634 3/20 0.38
▸ NOS2 P35228 2/20 0.38
▸ NOS3 P29474 1/20 0.38
▸ NOS1 P29475 1/20 0.38
▸ EPHX2 P34913 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ MAPK8 P45983 1/20 0.36
▸ MAPK9 P45984 1/20 0.36
▸ MAPK10 P53779 1/20 0.36
▸ FURIN P09958 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8759336 1.00 MEN1 (0.47) MEN1KMT2APRCPDPP7CTSC
SCHEMBL31487414 1.00 MEN1 (0.47) MEN1KMT2APRCPDPP7CTSC
SCHEMBL17711236 1.00 MEN1 (0.47) MEN1KMT2APRCPDPP7CTSC
SCHEMBL10650846 0.96 MEN1 (0.44) MEN1KMT2APRCPDPP7CTSC
SCHEMBL29421098 0.96 MEN1 (0.44) MEN1KMT2APRCPDPP7CTSC
SCHEMBL29496543 0.96 MEN1 (0.44) MEN1KMT2APRCPDPP7CTSC
Trifluoroacetic Acid SCHEMBL29808681 0.94 MEN1 (0.43) MEN1KMT2APRCPDPP7CTSC
SCHEMBL30973948 0.93 MEN1 (0.42) MEN1KMT2APRCPDPP7MAPK8
SCHEMBL29721158 0.92 MAPK8 (0.43) MEN1KMT2APRCPDPP7CTSC
SCHEMBL30712166 0.92 MAPK8 (0.43) MEN1KMT2APRCPDPP7CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103700-A1 REGULATION OF RAN TRANSLATION BY PKR AND EIF2A-P PATHWAYS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2026-04-16 — — US claimed
US-20260060913-A1 BIOACTIVE WALNUT PEPTIDES FOR TREATING HAIR LOSS L'OREAL (FR) 2026-03-05 — — US claimed
US-20260007756-A1 COMPOUND AND USE THEREOF COHERENT BIOPHARMA SUZHOU LTD (CN) 2026-01-08 — — US claimed
US-20250375466-A1 MANIPULATION OF EIF3 TO MODULATE REPEAT ASSOCIATED NON-ATG (RAN) TRANSLATION UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-12-11 — — US claimed
US-20250367115-A1 Excipients To Reduce the Viscosity of Antibody Formulations and Formulation Compositions AMGEN INC. (US) 2025-12-04 — — US claimed
US-12364707-B2 Manipulation of eIF3 to modulate repeat associated non-ATG (RAN) translation UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2025-07-22 — — US claimed
WO-2025092703-A1 PHOTOSENSITIZER CONJUGATE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF 同宜医药(苏州)有限公司 2025-05-08 — — WO claimed
CN-119909192-A Photosensitizer conjugate compound, pharmaceutical composition and application thereof 同宜医药(苏州)有限公司 2025-05-02 — — CN claimed
US-12257343-B2 Excipients to reduce the viscosity of antibody formulations and formulation compositions AMGEN INC. (US) 2025-03-25 — — US claimed
CN-119614675-A Wetting liquid formula for improving sample preservation effect 上海健采医疗器械有限公司 2025-03-14 — — CN claimed
EP-0565863-B1 Semi-synthetic glycosaminoglycans with heparin or heparan structure of alpha-L-iduronic-2-0-sulfate acid modified in position 2 ALFA WASSERMANN SPA (IT) 1997-06-18 — — EP claimed
EP-0565862-B1 Semi-synthetic glycosaminoglycans containing alpha-L-galacturonic acid substituted with nucleophilic radicals in position 3 ALFA WASSERMANN SPA (IT) 1997-06-18 — — EP claimed
EP-0618234-B1 Process for the synthesis of semisynthetic glycosaminoglycans with heparin or heparan structure modified in position 2 of the alpha-L-iduronic-2-0-sulfate acid ALFA WASSERMANN SPA (IT) 1997-06-04 — — EP claimed
US-5430133-A Semi-synthetic glycosaminoglycans with heparin or heparan structure of α-L-iduronic-2-O-sulfate acid modified in position 2 ALFA WASSERMANN S.P.A. (IT) 1995-07-04 — — US claimed
US-5410039-A Process for the synthesis of glycosaminoglycans containing α-L-galacturonic acid substituted with nucleophilic groups in position 3 ALFA WASSERMANN S.P.A. (IT) 1995-04-25 — — US claimed
US-5405949-A Process for the synthesis of glycosaminoglycans with heparin or heparan structure modified in position 2 of the α-L-iduronic-2-O-sulfate acid ALFA WASSERNANN S.P.A. (IT) 1995-04-11 — — US claimed
EP-0618235-A1 Process for the synthesis of semisynthetic glycosaminoglycans containig alpha-L-galacturonic acid substituted with nucleophilic radicals in position 3 ALFA WASSERMANN S.p.A. (IT) 1994-10-05 — — EP claimed
EP-0618234-A1 Process for the synthesis of semisynthetic glycosaminoglycans with heparin or heparan structure modified in position 2 of the alpha-L-iduronic-2-0-sulfate acid ALFA WASSERMANN S.p.A. (IT) 1994-10-05 — — EP claimed
EP-0565863-A2 Semi-synthetic glycosaminoglycans with heparin or heparan structure of alpha-L-iduronic-2-0-sulfate acid modified in position 2 ALFA WASSERMANN S.p.A. (IT) 1993-10-20 — — EP claimed
EP-0565862-A2 Semi-synthetic glycosaminoglycans containing alpha-L-galacturonic acid substituted with nucleophilic radicals in position 3 ALFA WASSERMANN S.p.A. (IT) 1993-10-20 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250367115-A1 Excipients To Reduce the Viscosity of Antibody Formulations and Formulation Compositions ARGLU1, ARG1, FCGRT MEN1 2259/4885KMT2A 2460/4885PRCP 73/4885
US-20260060913-A1 BIOACTIVE WALNUT PEPTIDES FOR TREATING HAIR LOSS TYR, CUTA, ARGLU1 MEN1 2073/4885KMT2A 4225/4885PRCP 4092/4885
US-20260007756-A1 COMPOUND AND USE THEREOF FOLH1, TRPV6, FOLR1 MEN1 1576/4885KMT2A 2977/4885PRCP 553/4885
US-12257343-B2 Excipients to reduce the viscosity of antibody formulations and formulation compositions ARGLU1, ARG1, FCGRT MEN1 2259/4885KMT2A 2460/4885PRCP 73/4885
US-20260103700-A1 REGULATION OF RAN TRANSLATION BY PKR AND EIF2A-P PATHWAYS EIF2A, EIF2AK1, EIF2AK3 MEN1 4735/4885KMT2A 1730/4885PRCP 1369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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