Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.51 |
| ▸ | NUDT1 | P36639 | 7/20 | 0.48 |
| ▸ | CD38 | P28907 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 4/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23148163 | 1.00 | TBK1 (0.51) | TBK1NUDT1CD38ARCCNC | |
| SCHEMBL23147722 | 0.87 | TBK1 (0.54) | TBK1NUDT1 | |
| SCHEMBL29721655 | 0.87 | TBK1 (0.54) | TBK1NUDT1 | |
| SCHEMBL29721623 | 0.85 | TBK1 (0.51) | TBK1NUDT1ARCDC7PIM1 | |
| SCHEMBL23148005 | 0.85 | TBK1 (0.51) | TBK1NUDT1ARCDC7PIM1 | |
| SCHEMBL23147769 | 0.85 | NUDT1 (0.49) | TBK1NUDT1CD38CCNCCDK8 | |
| SCHEMBL29722076 | 0.84 | NUDT1 (0.55) | TBK1NUDT1CD38CCNCCDK8 | |
| SCHEMBL23147659 | 0.84 | NUDT1 (0.50) | TBK1NUDT1CD38CCNCCDK8 | |
| SCHEMBL23147750 | 0.84 | NUDT1 (0.55) | TBK1NUDT1CD38CCNCCDK8 | |
| SCHEMBL29721944 | 0.84 | NUDT1 (0.50) | TBK1NUDT1CD38CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | claimed |
| EP-4034108-A1 | AZAINDOLE CARBOXAMIDE COMPOUNDS FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS | The Global Alliance for TB Drug Development, Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |