Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2970408 | 1.00 | CYP1A2 (0.33) | CYP1A2CYP2D6CYP2C19LMNAADRA2A | |
| SCHEMBL2963296 | 1.00 | CYP1A2 (0.33) | CYP1A2CYP2D6CYP2C19LMNAADRA2A | |
| SCHEMBL2974495 | 1.00 | CYP1A2 (0.33) | CYP1A2CYP2D6CYP2C19LMNAADRA2A | |
| SCHEMBL2960660 | 1.00 | CYP1A2 (0.33) | CYP1A2CYP2D6CYP2C19LMNAADRA2A | |
| SCHEMBL2964529 | 0.98 | ADRA2A (0.33) | CYP1A2CYP2D6CYP2C19LMNAADRA2A | |
| SCHEMBL2971828 | 0.94 | NPC1 (0.34) | ADRA2AADRA2BADRA2CPNMTHTR2A | |
| SCHEMBL2974541 | 0.88 | TRPA1 (0.34) | CYP1A2CYP2D6CYP2C19LMNAADRA2A | |
| SCHEMBL2970635 | 0.88 | TRPA1 (0.34) | CYP1A2CYP2D6CYP2C19LMNAADRA2A | |
| SCHEMBL2969538 | 0.88 | TRPA1 (0.34) | CYP1A2CYP2D6CYP2C19LMNAADRA2A | |
| SCHEMBL2974889 | 0.88 | TRPA1 (0.34) | CYP1A2CYP2D6CYP2C19LMNAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7763562-B2 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135597-A1 | Heteroatom bridged metallocene compounds for olefin polymerization | AP2M1, AP1M1, PYM1 | CYP1A2 2409/4885CYP2D6 2519/4885CYP2C19 3738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.