Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR2 | O95665 | 5/20 | 0.54 |
| ▸ | NTSR1 | P30989 | 5/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.54 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | CALCR | P30988 | 3/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723441 | 0.94 | CALCR (0.53) | NTSR1CRHR1CRHR2CALCROPRD1 | |
| SCHEMBL29723134 | 0.94 | CALCR (0.58) | CRHR1CRHR2CALCROPRD1 | |
| SCHEMBL29723274 | 0.94 | NTSR1 (0.51) | NTSR2NTSR1SORT1F2CXCL8 | |
| SCHEMBL29722989 | 0.93 | CALCR (0.55) | NTSR1CRHR1CRHR2CALCROPRD1 | |
| SCHEMBL29722981 | 0.92 | CXCL8 (0.50) | NTSR2NTSR1SORT1CRHR1CRHR2 | |
| SCHEMBL29723075 | 0.91 | CALCR (0.58) | NTSR2NTSR1SORT1CRHR1CRHR2 | |
| SCHEMBL29723129 | 0.89 | CALCR (0.56) | CRHR1CRHR2CALCROPRD1 | |
| SCHEMBL29723433 | 0.88 | F2 (0.50) | NTSR2NTSR1SORT1OPRD1F2 | |
| SCHEMBL31182968 | 0.87 | CALCR (0.65) | CRHR1CRHR2CALCR | |
| SCHEMBL29723009 | 0.84 | CALCR (0.50) | CRHR1CRHR2CALCROPRD1CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538543-B1 | PROTRANSDUZIN-S - AN ENHANCER OF GENE TRANSFER | PHARIS BIOTEC GMBH (DE) | 2022-06-08 | — | — | EP | claimed |
| EP-3538543-B1 | PROTRANSDUZIN-S - AN ENHANCER OF GENE TRANSFER | PHARIS BIOTEC GMBH (DE) | 2022-06-08 | — | — | EP | disclosed |