Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | BTK | Q06187 | 6/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 3/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22621309 | 1.00 | F10 (0.47) | F10MAP4K4BTKJAK3CA1 | |
| SCHEMBL19934556 | 1.00 | F10 (0.47) | F10MAP4K4BTKJAK3CA1 | |
| SCHEMBL19934557 | 0.91 | MAP4K4 (0.47) | F10MAP4K4BTKJAK3CA1 | |
| SCHEMBL29727404 | 0.91 | MAP4K4 (0.47) | F10MAP4K4BTKJAK3CA1 | |
| SCHEMBL22621256 | 0.91 | MAP4K4 (0.47) | F10MAP4K4BTKJAK3CA1 | |
| SCHEMBL22608005 | 0.88 | MAP4K4 (0.48) | F10MAP4K4BTKJAK3CA1 | |
| SCHEMBL19926339 | 0.88 | MAP4K4 (0.48) | F10MAP4K4BTKJAK3CA1 | |
| SCHEMBL4515184 | 0.86 | PIM1 (0.44) | F10MAPT | |
| SCHEMBL13713215 | 0.86 | OPRK1 (0.42) | F10BTKJAK3CA1CA2 | |
| SCHEMBL4514674 | 0.82 | PIM1 (0.40) | F10BTKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109923107-B | Process for preparing indole carboxamide compounds | 百时美施贵宝公司 | 2022-06-14 | — | — | CN | disclosed |