Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25039756 | 1.00 | ALDH1A1 (0.54) | ALDH1A1MAPTKDM4EMAPK1TSHR | |
| SCHEMBL25040532 | 0.97 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EMAPK1TSHR | |
| SCHEMBL29729346 | 0.97 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EMAPK1TSHR | |
| SCHEMBL25039579 | 0.94 | KDM4E (0.56) | ALDH1A1MAPTKDM4EMAPK1TSHR | |
| SCHEMBL25039578 | 0.94 | KDM4E (0.56) | ALDH1A1MAPTKDM4EMAPK1TSHR | |
| SCHEMBL31741747 | 0.83 | RAB9A (0.55) | ALDH1A1MAPTKDM4EMAPK1TSHR | |
| SCHEMBL29729350 | 0.83 | RAB9A (0.55) | ALDH1A1MAPTKDM4EMAPK1TSHR | |
| SCHEMBL25039181 | 0.83 | RAB9A (0.55) | ALDH1A1MAPTKDM4EMAPK1TSHR | |
| SCHEMBL23489020 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EMAPK1TSHR | |
| SCHEMBL30231993 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTKDM4EMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4069252-B1 | PDIA4 INHIBITORS AND USE THEREOF FOR INHIBITING SS-CELL PATHOGENESIS AND TREATING DIABETES | ACADEMIA SINICA (CN) | 2025-12-10 | — | — | EP | disclosed |
| CN-114761025-B | PDIA4 inhibitors and their use for inhibiting beta cell pathologies and for treating diabetes | 施明哲 | 2024-03-12 | — | — | CN | disclosed |
| CN-114761025-A | PDIA4 inhibitor and application thereof in inhibiting beta cell pathology and treating diabetes | 施明哲 | 2022-07-15 | — | — | CN | disclosed |