Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.69 |
| ▸ | CA2 | P00918 | 6/20 | 0.69 |
| ▸ | CA12 | O43570 | 5/20 | 0.69 |
| ▸ | CA7 | P43166 | 5/20 | 0.69 |
| ▸ | CA9 | Q16790 | 5/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.69 |
| ▸ | XDH | P47989 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976862 | 1.00 | CA1 (0.69) | CA1CA2CA12CA7CA9 | |
| SCHEMBL5847115 | 0.86 | EGFR (0.63) | CA1CA2CA12CA7CA9 | |
| SCHEMBL944597 | 0.85 | CA1 (0.69) | CA1CA2CA12CA7CA9 | |
| SCHEMBL550572 | 0.84 | CA1 (0.57) | CA1CA2CA12CA7CA9 | |
| Methyl Protocatechuate SCHEMBL29360855 | 0.82 | CA1 (1.00) | CA1CA2CA12CA7CA9 | |
| SCHEMBL15099889 | 0.82 | CA1 (0.77) | CA1CA2CA12CA7CA9 | |
| Methyl Protocatechuate SCHEMBL38624 | 0.82 | CA1 (1.00) | CA1CA2CA12CA7CA9 | |
| SCHEMBL31525599 | 0.81 | CA12 (0.59) | CA1CA2CA12CA7CA9 | |
| SCHEMBL1459771 | 0.81 | TDP1 (0.53) | CA1CA2CA12CA7CA9 | |
| SCHEMBL27707943 | 0.81 | KDM4E (0.58) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119059895-A | Preparation method of 2,2 '-dihydroxybiphenyl-4, 4' -dicarboxylic acid | 黑龙江省科学院石油化学研究院 | 2024-12-03 | — | — | CN | disclosed |
| EP-4262796-A1 | MACROCYCLES AND THEIR USE | Blossomhill Therapeutics, Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-4069708-A1 | SSTR5 ANTAGONISTS | Kallyope, Inc. (US) | 2022-10-12 | — | — | EP | disclosed |
| EP-4069702-A1 | SSTR5 ANTAGONISTS | Kallyope, Inc. (US) | 2022-10-12 | — | — | EP | disclosed |
| WO-2022133037-A1 | MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2022-06-23 | — | — | WO | disclosed |