Methyl Protocatechuate

Methyl Protocatechuate

SCHEMBL38624

COC(=O)c1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 1.00
CA2 P00918 7/20 1.00
CA12 O43570 6/20 1.00
CA7 P43166 6/20 1.00
CA9 Q16790 6/20 1.00
CA14 Q9ULX7 6/20 1.00
XDH P47989 2/20 1.00
KDM4E B2RXH2 5/20 0.67
MAPT P10636 3/20 0.67
LMNA P02545 2/20 0.67
ALDH1A1 P00352 2/20 0.67
HPGD P15428 2/20 0.67
HSD17B10 Q99714 2/20 0.67
MEN1 O00255 1/20 0.67
TP53 P04637 1/20 0.67
ALOX15 P16050 1/20 0.67
ALOX12 P18054 1/20 0.67
HTT P42858 1/20 0.67
KMT2A Q03164 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Protocatechuate SCHEMBL29360855 1.00 CA1 (1.00) CA1CA2CA12CA7CA9
Methyl Protocatechuate SCHEMBL9132223 0.92 CA12 (0.85) CA1CA2CA12CA7CA9
SCHEMBL9426870 0.88 CA12 (0.77) CA1CA2CA12CA7CA9
SCHEMBL9132227 0.88 CA12 (0.77) CA1CA2CA12CA7CA9
SCHEMBL15099889 0.87 CA1 (0.77) CA1CA2CA12CA7CA9
SCHEMBL172476 0.83 CA1 (0.71) CA1CA2CA12CA7CA9
SCHEMBL403210 0.83 CA12 (0.71) CA1CA2CA12CA7CA9
SCHEMBL29501115 0.83 CA12 (0.71) CA1CA2CA12CA7CA9
SCHEMBL30809635 0.83 CA1 (0.71) CA1CA2CA12CA7CA9
SCHEMBL162631 0.83 CA12 (0.71) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 747 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260055051-A1 Compound with anti-tumor activity, preparation method therefor, and use thereof OCEAN UNIV CHINA (CN) 2026-02-26 US claimed
CN-116763858-B Application of radix tetrastigme protocatechuic acid methyl ester and isorhamnetin in preparing anti-inflammatory drugs 浙江五养堂中药集团有限公司 2025-05-30 CN claimed
CN-119745708-A Application of 3, 4-dihydroxybenzoic acid methyl ester in whitening 云南中医药大学 2025-04-04 CN claimed
CN-116763859-B Application of radix tetrastigme extract in preparation of anti-inflammatory drugs 莉医中医健康管理(丽水)有限公司 2025-01-10 CN claimed
CN-119139371-A Pseudo-ginseng active composition, meal replacement powder and application thereof in improving intestinal microecology, losing weight, reducing blood sugar and reducing blood fat 王晓娟 2024-12-17 CN claimed
CN-119125331-A Kit, method and application of composition for simultaneously measuring 11 benzoate and metabolites thereof and content of chlorine-containing antibacterial agent 湖南凯莱谱生物科技有限公司 2024-12-13 CN claimed
CN-118948826-A Application of protocatechuic acid methyl ester in preparation of medicine for improving intestinal barrier 湖北中医药大学 2024-11-15 CN claimed
CN-116889581-B Preparation method of pseudo-ginseng active composition 中科重生(雄安)生物科技有限公司 2024-08-30 CN claimed
CN-118515875-A Water reducer of alkali slag cementing material and preparation method thereof 江苏苏博特新材料股份有限公司 2024-08-20 CN claimed
CN-118489806-A Application of polyphenol in preparation of preparation for preventing and/or relieving intestinal immune stress or intestinal injury caused by zinc overload of animals 浙江大学 2024-08-16 CN claimed
CN-110133128-A The method for detecting antibiotic antiseptic in environment water 上海大学 2019-08-16 CN claimed
CN-106565533-B The organogel factor, the organogel and preparation method thereof with double-response 深圳大学 2018-07-31 CN claimed
CN-102718650-A 2-(2- hydroxyl-5-(methoxycarbonyl) phenoxyl) benzoic acid as well as preparation method and application thereof SOUTH CHINA BOTAN GARDEN CAS 2012-10-10 CN claimed
US-7838186-B2 Photoconductors containing charge transport chelating components XEROX CORPORATION (US) 2010-11-23 US claimed
US-20100168279-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS HENKEL AG & CO. KGAA (DE) 2010-07-01 US claimed
EP-2001924-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS National Starch and Chemical Investment Holding Corporation (US) 2008-12-17 EP claimed
US-20080286670-A1 Photoconductors containing charge transport chelating components XEROX CORPORATION 2008-11-20 US claimed
WO-2007114822-A1 THERMALLY CURABLE EPOXY-AMINE BARRIER SEALANTS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2007-10-11 WO claimed
US-5438052-A Cephalosporin derivatives HOFFMANN-LA ROCHE INC. (US) 1995-08-01 US claimed
US-5383050-A Optical waveguide device HOECHST AKTIENGESELLSCHAFT (DE) 1995-01-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260055051-A1 Compound with anti-tumor activity, preparation method therefor, and use thereof RCC2, WEE2, MET CA1 549/4885CA2 754/4885CA12 374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.