Methyl Protocatechuate

Methyl Protocatechuate

SCHEMBL29360855

COC(=O)c1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 1.00
CA2 P00918 7/20 1.00
CA12 O43570 6/20 1.00
CA7 P43166 6/20 1.00
CA9 Q16790 6/20 1.00
CA14 Q9ULX7 6/20 1.00
XDH P47989 2/20 1.00
KDM4E B2RXH2 5/20 0.67
MAPT P10636 3/20 0.67
LMNA P02545 2/20 0.67
ALDH1A1 P00352 2/20 0.67
HPGD P15428 2/20 0.67
HSD17B10 Q99714 2/20 0.67
MEN1 O00255 1/20 0.67
TP53 P04637 1/20 0.67
ALOX15 P16050 1/20 0.67
ALOX12 P18054 1/20 0.67
HTT P42858 1/20 0.67
KMT2A Q03164 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Protocatechuate SCHEMBL38624 1.00 CA1 (1.00) CA1CA2CA12CA7CA9
Methyl Protocatechuate SCHEMBL9132223 0.92 CA12 (0.85) CA1CA2CA12CA7CA9
SCHEMBL9426870 0.88 CA12 (0.77) CA1CA2CA12CA7CA9
SCHEMBL9132227 0.88 CA12 (0.77) CA1CA2CA12CA7CA9
SCHEMBL15099889 0.87 CA1 (0.77) CA1CA2CA12CA7CA9
SCHEMBL172476 0.83 CA1 (0.71) CA1CA2CA12CA7CA9
SCHEMBL403210 0.83 CA12 (0.71) CA1CA2CA12CA7CA9
SCHEMBL29501115 0.83 CA12 (0.71) CA1CA2CA12CA7CA9
SCHEMBL30809635 0.83 CA1 (0.71) CA1CA2CA12CA7CA9
SCHEMBL162631 0.83 CA12 (0.71) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746912-A1 ORGANIC CYTOTOXIN OLIGOMERS AND USES THEREOF AS A PAYLOAD IN ANTIBODY-DRUG CONJUGATES Simris Biologics GmbH (DE) 2026-05-27 EP claimed
EP-4577248-A1 A METHOD OF MODIFYING AN ORGANIC CYTOTOXIN FOR USE AS A PAYLOAD IN AN ANTIBODY-DRUG CONJUGATE AND MODIFIED ORGANIC CYTOTOXINS DERIVED THEREFROM Simris Biologics GmbH (DE) 2025-07-02 EP claimed
CN-119789876-A Method of modifying organic cytotoxins for use as payloads in antibody-drug conjugates and modified organic cytotoxins derived therefrom 辛利斯生物制药有限责任公司 2025-04-08 CN claimed
CN-119745708-A Application of 3, 4-dihydroxybenzoic acid methyl ester in whitening 云南中医药大学 2025-04-04 CN claimed
CN-119390606-A Photo-cured mussel bionic acylhydrazone, and preparation method and application thereof 华南农业大学 2025-02-07 CN claimed
WO-2025021727-A1 ORGANIC CYTOTOXIN OLIGOMERS AND USES THEREOF AS A PAYLOAD IN ANTIBODY-DRUG CONJUGATES SIMRIS BIOLOGICS GMBH (DE) 2025-01-30 WO claimed
EP-4494656-A1 ORGANIC CYTOTOXIN OLIGOMERS AND USES THEREOF AS A PAYLOAD IN ANTIBODY-DRUG CONJUGATES Simris Biologics GmbH (DE) 2025-01-22 EP claimed
CN-119061024-A MdHb1 gene and application of coded protein thereof in regulating postharvest apple fruit softening process 山东农业大学 2024-12-03 CN claimed
WO-2024209462-A1 ANTI-BIOFILM POLYMER COMPOSITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-10-10 WO claimed
CN-118489806-A Application of polyphenol in preparation of preparation for preventing and/or relieving intestinal immune stress or intestinal injury caused by zinc overload of animals 浙江大学 2024-08-16 CN claimed
CN-118255663-A Extraction method and application of 3, 4-dihydroxymethyl benzoate 大理大学 2024-06-28 CN claimed
CN-115838322-B Polymerization inhibiting composition for olefin compounds and polymerization inhibiting method 杭州唯铂莱生物科技有限公司 2024-03-29 CN claimed
CN-115181096-B 3TC-PA compound bonded through ester bonds and application thereof 湖北大学 2024-03-19 CN claimed
CN-117683836-A Methods for modifying microcystins and arthrosrottoxins 辛利斯生物制药有限责任公司 2024-03-12 CN claimed
WO-2024046929-A1 A METHOD OF MODIFYING AN ORGANIC CYTOTOXIN FOR USE AS A PAYLOAD IN AN ANTIBODY-DRUG CONJUGATE AND MODIFIED ORGANIC CYTOTOXINS DERIVED THEREFROM SIMRIS BIOLOGICS GMBH (DE) 2024-03-07 WO claimed
CN-116768564-A Lining concrete for large-section tunnel and preparation method thereof 长江水利委员会长江科学院 2023-09-19 CN claimed
CN-116715674-A Method for extracting various monomer compounds with anti-inflammatory activity from radix Berchemiae Giraldianae and application thereof 广西国际壮医医院 2023-09-08 CN claimed
CN-116236539-A Complex extract of cheilobium axillarm, composition containing the same and application thereof 赖立民 2023-06-09 CN claimed
EP-4746912-A1 ORGANIC CYTOTOXIN OLIGOMERS AND USES THEREOF AS A PAYLOAD IN ANTIBODY-DRUG CONJUGATES Simris Biologics GmbH (DE) 2026-05-27 EP disclosed
WO-2022019949-A1 ENZYMES AND METHODS FOR PRODUCTION OF MALONIC ACID AND DERIVATIVES THEREOF CARGILL, INCORPORATED (US) 2022-01-27 WO disclosed