SCHEMBL2973241

SCHEMBL2973241

C=C(C)C(=O)N1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1

nearest known ligand 0.82

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.82
ALDH1A1 P00352 4/20 0.82
LMNA P02545 3/20 0.71
HSD17B10 Q99714 3/20 0.71
HPGD P15428 2/20 0.71
MAPT P10636 1/20 0.71
CYP1A2 P05177 1/20 0.69
TOP2A P11388 1/20 0.69
CYP2C9 P11712 1/20 0.69
TOP2B Q02880 1/20 0.69
PIK3CG P48736 7/20 0.64
PIK3CD O00329 5/20 0.64
PIK3R1 P27986 5/20 0.64
PIK3CA P42336 5/20 0.64
HTT P42858 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350842 0.90 KDM4E (1.00) KDM4EALDH1A1LMNAHSD17B10HPGD
SCHEMBL10809240 0.90 KDM4E (1.00) KDM4EALDH1A1LMNAHSD17B10HPGD
SCHEMBL21160033 0.87 KDM4E (0.77) KDM4EALDH1A1LMNAHSD17B10HPGD
SCHEMBL825059 0.86 KDM4E (0.92) KDM4EALDH1A1LMNAHSD17B10HPGD
SCHEMBL10959265 0.86 KDM4E (0.78) KDM4EALDH1A1LMNAHSD17B10HPGD
SCHEMBL10807306 0.86 KDM4E (0.81) KDM4EALDH1A1LMNAHSD17B10HPGD
SCHEMBL13040619 0.86 KDM4E (0.71) KDM4EALDH1A1LMNAHSD17B10HPGD
SCHEMBL29576608 0.86 ALDH1A1 (0.81) KDM4EALDH1A1LMNAHSD17B10HPGD
SCHEMBL2780752 0.86 ALDH1A1 (0.81) KDM4EALDH1A1LMNAHSD17B10HPGD
SCHEMBL10924388 0.85 KDM4E (0.80) KDM4EALDH1A1LMNAHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7777033-B2 Monomer with anti-microbial character, polymer using the same, and manufacturing method thereof MICRO SCIENCE TECH CO., LTD. (KR) 2010-08-17 US claimed
US-20080188655-A1 Monomer With Anti-Microbial Character, Polymer Using The Same, And Manufacturing Method Thereof MICRO SCIENCE TECH CO., LTD. (KR) 2008-08-07 US claimed
US-20100278920-A1 Polyacrylate Nanoparticle Drug Delivery UNIVERSITY OF SOUTH FLORIDA (US) 2010-11-04 US disclosed
US-20100278920-A1 Polyacrylate Nanoparticle Drug Delivery UNIVERSITY OF SOUTH FLORIDA (US) 2010-11-04 US disclosed
US-7777033-B2 Monomer with anti-microbial character, polymer using the same, and manufacturing method thereof MICRO SCIENCE TECH CO., LTD. (KR) 2010-08-17 US disclosed
US-20080188655-A1 Monomer With Anti-Microbial Character, Polymer Using The Same, And Manufacturing Method Thereof MICRO SCIENCE TECH CO., LTD. (KR) 2008-08-07 US disclosed
US-7361719-B2 Monomer with anti-microbial character, polymer using the same, and manufacturing method thereof MICRO SCIENCE TECH CO., LTD. (KR) 2008-04-22 US disclosed
US-20050176905-A1 Monomer with anti-microbial character, polymer using the same, and manufacturing method thereof MICRO SCIENCE TECH CO., LTD. (KR) 2005-08-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080188655-A1 Monomer With Anti-Microbial Character, Polymer Using The Same, And Manufacturing Method Thereof PCNA, HSF1, TERB1 KDM4E 1725/4885ALDH1A1 2231/4885LMNA 2084/4885
US-20100278920-A1 Polyacrylate Nanoparticle Drug Delivery ABCC1, PARG, SLC11A2 KDM4E 758/4885ALDH1A1 1936/4885LMNA 451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.