Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 16/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.50 |
| ▸ | PGR | P06401 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22491353 | 1.00 | MGLL (0.56) | MGLLNR3C2NR3C1PGRLMNA | |
| SCHEMBL29734574 | 0.89 | NR3C2 (0.49) | MGLLNR3C2NR3C1LMNA | |
| SCHEMBL22491346 | 0.89 | NR3C2 (0.49) | MGLLNR3C2NR3C1LMNA | |
| SCHEMBL22491458 | 0.84 | MGLL (0.56) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL29734537 | 0.84 | MGLL (0.56) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL22491572 | 0.83 | MGLL (0.57) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL29734607 | 0.83 | MGLL (0.57) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL22491514 | 0.83 | MGLL (0.56) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL29734583 | 0.83 | MGLL (0.56) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL22773216 | 0.81 | MGLL (0.53) | MGLLNR3C2NR3C1PGRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717477-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2022-07-20 | — | — | EP | disclosed |