Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 8/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22491514 | 1.00 | MGLL (0.56) | MGLLNR3C2NR3C1PGRHTR2A | |
| SCHEMBL29734537 | 0.93 | MGLL (0.56) | MGLLNR3C2NR3C1PGRHTR2A | |
| SCHEMBL22491458 | 0.93 | MGLL (0.56) | MGLLNR3C2NR3C1PGRHTR2A | |
| SCHEMBL22491463 | 0.84 | NR3C2 (0.46) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL29734496 | 0.84 | NR3C2 (0.46) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL22491353 | 0.83 | MGLL (0.56) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL29734577 | 0.83 | MGLL (0.56) | MGLLNR3C2NR3C1PGR | |
| SCHEMBL18619403 | 0.80 | HTT (0.54) | HTR2ADRD3HTR1AHTR1F | |
| SCHEMBL22491520 | 0.80 | MGLL (0.57) | MGLLNR3C2NR3C1PGRHTR1A | |
| SCHEMBL29734499 | 0.80 | MGLL (0.57) | MGLLNR3C2NR3C1PGRHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3717477-B1 | NEW HETEROCYCLIC COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2022-07-20 | — | — | EP | disclosed |