Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28556096 | 1.00 | SCN9A (0.39) | SCN9AALDH1A1LMNAMAPTTSHR | |
| SCHEMBL28552935 | 0.87 | SCN8A (0.36) | SCN9AALDH1A1TSHR | |
| SCHEMBL29736394 | 0.87 | SCN8A (0.36) | SCN9AALDH1A1TSHR | |
| SCHEMBL28561090 | 0.85 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1094589 | 0.83 | SCN9A (0.49) | SCN9AMAPT | |
| SCHEMBL1093593 | 0.82 | SCN9A (0.40) | SCN9AALDH1A1MAPTTSHR | |
| SCHEMBL29736437 | 0.82 | SCN9A (0.40) | SCN9AALDH1A1MAPTTSHR | |
| SCHEMBL1094007 | 0.81 | SCN9A (0.48) | SCN9A | |
| SCHEMBL18882727 | 0.80 | RORC (0.37) | SCN9AALDH1A1LMNATSHR | |
| SCHEMBL28912753 | 0.80 | SCN9A (0.39) | SCN9AALDH1A1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759559-B | Sulfonamide compounds as sodium channel blockers and uses thereof | 成都康弘药业集团股份有限公司 | 2022-08-12 | — | — | CN | disclosed |