SCHEMBL29737836

SCHEMBL29737836

NCCCC[C@H](N)C(=O)N[C@@H](CO)C(=O)NCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ NMT1 P30419 7/20 0.45
▸ NMT2 O60551 6/20 0.45
▸ GSR P00390 1/20 0.45
▸ DPP8 Q6V1X1 2/20 0.44
▸ DPP9 Q86TI2 2/20 0.44
▸ DPP7 Q9UHL4 2/20 0.44
▸ GNAI3 P08754 1/20 0.43
▸ GNAO1 P09471 1/20 0.43
▸ GNAI1 P63096 1/20 0.43
▸ PTGS1 P23219 1/20 0.43
▸ GSTK1 Q9Y2Q3 1/20 0.43
▸ MMP2 P08253 1/20 0.41
▸ TERT O14746 1/20 0.40
▸ FOLH1 Q04609 1/20 0.39
▸ DPP4 P27487 1/20 0.39
▸ GLO1 Q04760 1/20 0.38
▸ TLR2 O60603 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29737833 0.95 NMT1 (0.45) NMT1NMT2GSRDPP8DPP9
SCHEMBL30123144 0.92 NMT1 (0.46) NMT1NMT2GSRDPP8DPP9
SCHEMBL18234163 0.92 NMT1 (0.51) NMT1NMT2PTGS1GSTK1MMP2
SCHEMBL30513899 0.92 PTGS1 (0.52) NMT1NMT2GSRDPP8DPP9
SCHEMBL31665964 0.91 NMT1 (0.50) NMT1NMT2PTGS1GSTK1MMP2
SCHEMBL18234267 0.91 NMT1 (0.53) NMT1NMT2PTGS1GSTK1TERT
SCHEMBL29397470 0.91 GSR (0.47) NMT1NMT2GSRDPP8DPP9
SCHEMBL29569320 0.90 GSR (0.46) NMT1NMT2GSRDPP8DPP9
SCHEMBL29569055 0.90 GSR (0.46) NMT1NMT2GSRDPP8DPP9
SCHEMBL29569009 0.90 GSR (0.46) NMT1NMT2GSRDPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12128110-B2 Transglutaminase conjugation method and linker PAUL SCHERRER INSTITUT (CH) 2024-10-29 — — US claimed
US-20250161479-A1 TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER PAUL SCHERRER INSTITUT (CH) 2025-05-22 — — US disclosed
US-12128110-B2 Transglutaminase conjugation method and linker PAUL SCHERRER INSTITUT (CH) 2024-10-29 — — US disclosed
US-20240350656-A1 TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER PAUL SCHERRER INSTITUT (CH) 2024-10-24 — — US disclosed
EP-4370150-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS Intervet International B.V. (NL) 2024-05-22 — — EP disclosed
WO-2023285489-A1 OVERCOMING ANTIBODY-INTERFERENCE IN AVIANS INTERVET INTERNATIONAL B.V. (NL) 2023-01-19 — — WO disclosed
CN-114891759-A Wx mutant protein based on gene editing technology and application of gene thereof in plant breeding 江苏省农业科学院 2022-08-12 — — CN disclosed
CN-111197034-B Wx mutant protein based on gene editing technology and application of gene thereof in plant breeding 江苏省农业科学院 2022-07-29 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250161479-A1 TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER TGM3, TGM2, TGM1 NMT1 75/4885NMT2 76/4885GSR 781/4885
US-12128110-B2 Transglutaminase conjugation method and linker TGM3, TGM2, TGM1 NMT1 76/4885NMT2 80/4885GSR 716/4885
US-20240350656-A1 TRANSGLUTAMINASE CONJUGATION METHOD AND LINKER TGM3, TGM2, TGM1 NMT1 76/4885NMT2 79/4885GSR 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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