Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.49 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | TLR4 | O00206 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558176 | 1.00 | PARP10 (0.49) | PARP10PARP15SIGMAR1TLR4TLR2 | |
| SCHEMBL9112139 | 0.88 | SIGMAR1 (0.49) | PARP10PARP15SIGMAR1TLR4TLR2 | |
| SCHEMBL30140325 | 0.88 | SIGMAR1 (0.49) | PARP10PARP15SIGMAR1TLR4TLR2 | |
| SCHEMBL13836687 | 0.86 | SIGMAR1 (0.52) | PARP10PARP15SIGMAR1TLR4TLR2 | |
| SCHEMBL2338053 | 0.86 | HPGD (0.49) | TLR4TLR2ATMTDP1MAPT | |
| SCHEMBL28034902 | 0.82 | SIGMAR1 (0.49) | PARP10PARP15SIGMAR1TLR4TLR2 | |
| SCHEMBL2651222 | 0.82 | SIGMAR1 (0.46) | SIGMAR1TLR4TLR2 | |
| Tert-Butyl Formate SCHEMBL27857829 | 0.81 | SLC6A2 (0.43) | PARP10PARP15SIGMAR1TLR4TLR2 | |
| SCHEMBL27857828 | 0.81 | SIGMAR1 (0.42) | PARP10PARP15SIGMAR1LMNARAPGEF3 | |
| SCHEMBL30137642 | 0.81 | SIGMAR1 (0.45) | PARP10PARP15SIGMAR1TLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115611897-A | Compounds as RSK2 inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |