Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | TLR4 | O00206 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 6/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13836687 | 0.86 | SIGMAR1 (0.52) | SIGMAR1TLR4TLR2PARP15PARP10 | |
| SCHEMBL2558176 | 0.82 | PARP10 (0.49) | SIGMAR1TLR4TLR2PARP15PARP10 | |
| SCHEMBL29739999 | 0.82 | PARP10 (0.49) | SIGMAR1TLR4TLR2PARP15PARP10 | |
| SCHEMBL27038419 | 0.79 | SIGMAR1 (0.49) | SIGMAR1TLR4TLR2PARP15PARP10 | |
| SCHEMBL30140325 | 0.79 | SIGMAR1 (0.49) | SIGMAR1TLR4TLR2PARP15PARP10 | |
| SCHEMBL2552169 | 0.79 | SIGMAR1 (0.49) | SIGMAR1TLR4TLR2PARP15PARP10 | |
| SCHEMBL9112139 | 0.79 | SIGMAR1 (0.49) | SIGMAR1TLR4TLR2PARP15PARP10 | |
| SCHEMBL5765504 | 0.79 | SIGMAR1 (0.52) | SIGMAR1TLR4TLR2PARP15PARP10 | |
| SCHEMBL17493045 | 0.79 | DTYMK (0.48) | SIGMAR1TLR4TLR2PARP15PARP10 | |
| SCHEMBL2651222 | 0.79 | SIGMAR1 (0.46) | SIGMAR1TLR4TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121405-A | Dicarboxylic acid compound | DAIICHI SANKYO CO LTD | 2015-12-02 | — | — | CN | disclosed |