Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2977679 | 0.81 | ALDH1A1 (0.44) | CYP1A2MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL1256788 | 0.79 | KDM4E (0.45) | KDM4EPOLBLMNAMETAP1CYP1A2 | |
| SCHEMBL12470406 | 0.78 | KDM4E (0.43) | SQORGRM5KDM4EPOLBLMNA | |
| SCHEMBL28619834 | 0.78 | KDM4E (0.43) | KDM4EPOLBLMNAMETAP1CYP1A2 | |
| SCHEMBL5671301 | 0.77 | ALDH1A1 (0.41) | KDM4EPOLBLMNACYP1A2HIF1A | |
| SCHEMBL30965294 | 0.76 | KDM4E (0.42) | KDM4EPOLBLMNAMETAP1CYP1A2 | |
| SCHEMBL29141638 | 0.76 | KDM4E (0.42) | KDM4EPOLBLMNAMETAP1CYP1A2 | |
| SCHEMBL11283887 | 0.76 | KDM4E (0.45) | KDM4EPOLBLMNAMETAP1CYP1A2 | |
| SCHEMBL608226 | 0.75 | KDM4E (0.48) | KDM4EPOLBLMNAMETAP1CYP1A2 | |
| SCHEMBL8721465 | 0.74 | KDM4E (0.46) | KDM4EPOLBLMNAMETAP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229377-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | Wyeth LLC (US) | 2010-09-22 | — | — | EP | claimed |
| WO-2009076602-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | WYETH (US) | 2009-06-18 | — | — | WO | claimed |