Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | USP8 | P40818 | 1/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686077 | 1.00 | NOTUM (0.47) | NOTUMCA1CA2USP8USP7 | |
| SCHEMBL31686453 | 1.00 | NOTUM (0.47) | NOTUMCA1CA2USP8USP7 | |
| SCHEMBL1872875 | 0.89 | MAOB (0.46) | NOTUMCA1CA2USP8USP7 | |
| SCHEMBL29741207 | 0.89 | MAOB (0.46) | NOTUMCA1CA2USP8USP7 | |
| SCHEMBL30522676 | 0.77 | NOTUM (0.44) | NOTUMCA1CA2USP8USP7 | |
| SCHEMBL11763794 | 0.77 | CES1 (0.55) | NOTUMCA1CA2USP8USP7 | |
| SCHEMBL28633125 | 0.76 | NOTUM (0.43) | NOTUMCA1CA2ALDH1A1GRM5 | |
| SCHEMBL1861726 | 0.76 | ALDH1A1 (0.48) | USP8USP7ALDH1A1GAAKDM4E | |
| SCHEMBL4825821 | 0.74 | NOTUM (0.49) | NOTUMALDH1A1KDM4EHPGDESR2 | |
| SCHEMBL25168174 | 0.73 | ALDH1A1 (0.42) | ALDH1A1GAAKDM4EHPGDNISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114411184-A | Electrochemical preparation method of intermediate of ozapimod | 湖南大学 | 2022-04-29 | — | — | CN | claimed |
| CN-113698319-A | Preparation method of ozapimod intermediate | 偶极医药科技(徐州)有限公司 | 2021-11-26 | — | — | CN | claimed |
| CN-113214111-A | Preparation method of 3- (2-cyanophenyl) propionic acid and 4-cyano-1-indanone | 上海立科化学科技有限公司 | 2021-08-06 | — | — | CN | claimed |
| US-20210108245-A1 | Enantioselective Biocatalytic Preparation of 4-Cyano-Substituted 1-Aminoindane and Ozanimod | PHARMAZELL GMBH (DE) | 2021-04-15 | — | — | US | claimed |
| EP-3775253-A1 | ENANTIOSELECTIVE BIOCATALYTIC PREPARATION OF 4-CYANO-SUBSTITUTED 1-AMINOINDANE AND OZANIMOD | Pharmazell GmbH (DE) | 2021-02-17 | — | — | EP | claimed |
| CN-111971398-A | Enantioselective biocatalytic preparation of 4-cyano-substituted 1-aminoindan and azanidod | 泽尔制药有限公司 | 2020-11-20 | — | — | CN | claimed |
| CN-111704559-A | Method for preparing 2, 3-dihydro-1-oxo-1H-indene-4-carbonitrile | 重庆医药高等专科学校 | 2020-09-25 | — | — | CN | claimed |
| CN-110627683-A | Preparation method of indanone intermediate | 广东东阳光药业有限公司 | 2019-12-31 | — | — | CN | claimed |
| CN-110615747-A | Preparation method of indane intermediate | 广东东阳光药业有限公司 | 2019-12-27 | — | — | CN | claimed |
| WO-2019197571-A1 | ENANTIOSELECTIVE BIOCATALYTIC PREPARATION OF 4-CYANO-SUBSTITUTED 1-AMINOINDANE AND OZANIMOD | UNIVERSITÄT BIELEFELD (DE) | 2019-10-17 | — | — | WO | claimed |
| EP-3553179-A1 | ENANTIOSELECTIVE BIOCATALYTIC PREPARATION OF 4-CYANO-SUBSTITUTED 1-AMINOINDANE AND OZANIMOD | Universität Bielefeld (DE) | 2019-10-16 | — | — | EP | claimed |
| WO-2019058290-A1 | IMPROVED PROCESS FOR THE PREPARATION OF OZANIMOD Α-AMINO COMPOUND | SUVEN LIFE SCIENCES LIMITED (IN) | 2019-03-28 | — | — | WO | claimed |
| CN-117843529-B | Resolution method of ozagrel hydrochloride intermediate and preparation method of ozagrel hydrochloride | Beijing Sunshine Nuohe Pharmaceutical Research Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-114411184-B | Electrochemical preparation method of ozagrel intermediate | 湖南大学 | 2026-05-15 | — | — | CN | disclosed |
| EP-4126829-B1 | SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS | RECEPTOS LLC (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-3518922-B1 | COMPOUNDS AND METHODS FOR TREATING LUPUS | RECEPTOS LLC (US) | 2026-02-11 | — | — | EP | disclosed |
| EP-0456133-A1 | Hydrazones | CIBA-GEIGY AG (CH) | 1991-11-13 | — | — | EP | disclosed |
| EP-0369944-A1 | Substituted oxadiamino butanes | CIBA-GEIGY AG (CH) | 1990-05-23 | — | — | EP | disclosed |
| EP-0357742-A1 | NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES. | ROUSSEL UCLAF (FR) | 1990-03-14 | — | — | EP | disclosed |
| WO-1989008096-A1 | NEW PYRETHRINOID ESTERS CARRYING AN INDANYL RING, PREPARATION METHOD AND APPLICATION AS PESTICIDES | ROUSSEL-UCLAF (FR) | 1989-09-08 | — | — | WO | disclosed |