Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.35 |
| ▸ | SELE | P16581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30514529 | 0.89 | ALDH1A1 (0.41) | KMT2AMEN1CREBBPEP300ALDH1A1 | |
| SCHEMBL24570312 | 0.89 | ALDH1A1 (0.41) | KMT2AMEN1CREBBPEP300ALDH1A1 | |
| SCHEMBL15560839 | 0.89 | MEN1 (0.55) | KMT2AMEN1CREBBPHRH3EP300 | |
| SCHEMBL29746500 | 0.83 | KDM4C (0.36) | KMT2AMEN1CREBBPEP300ALDH1A1 | |
| SCHEMBL27418998 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1CREBBPEP300ALDH1A1 | |
| SCHEMBL378049 | 0.79 | KMT2A (0.43) | KMT2AMEN1CREBBPALDH1A1KDM4E | |
| SCHEMBL3811958 | 0.76 | KMT2A (0.64) | KMT2AMEN1CREBBPEP300ALDH1A1 | |
| SCHEMBL4309447 | 0.74 | CREBBP (0.59) | KMT2AMEN1CREBBPEP300ALDH1A1 | |
| SCHEMBL26926590 | 0.73 | HRH3 (0.55) | HRH3ALDH1A1KDM4EKDM4C | |
| SCHEMBL4505041 | 0.73 | MEN1 (0.54) | KMT2AMEN1CREBBPEP300ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022138812-A1 | TETRAHYDRO THIENOPYRIDINE SULFONAMIDE COMPOUND | モジュラス株式会社 | 2022-06-30 | — | — | WO | disclosed |