Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 3/20 | 0.56 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.44 |
| ▸ | CACNG8 | Q8WXS5 | 3/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26613466 | 1.00 | AHR (0.58) | AHRPGRPDE3BPDE3ACMA1 | |
| SCHEMBL1900155 | 0.78 | AHR (0.77) | AHRPGRPDE3BPDE3ACMA1 | |
| SCHEMBL154614 | 0.76 | AHR (1.00) | AHRPGRPDE3BPDE3ACMA1 | |
| SCHEMBL29746115 | 0.74 | MAPT (0.53) | PDE3BPDE3ACYP1A2CYP11B1CYP11B2 | |
| SCHEMBL26613480 | 0.74 | MAPT (0.58) | PDE3BPDE3ACYP1A2CYP11B1CYP11B2 | |
| SCHEMBL26613471 | 0.74 | MAPT (0.53) | PDE3BPDE3ACYP1A2CYP11B1CYP11B2 | |
| SCHEMBL15682858 | 0.74 | AHR (0.54) | AHRPGRPDE3BPDE3ACMA1 | |
| SCHEMBL29746163 | 0.74 | MAPT (0.58) | PDE3BPDE3ACYP1A2CYP11B1CYP11B2 | |
| SCHEMBL18189562 | 0.73 | AHR (0.69) | AHRPGRPDE3BPDE3ACMA1 | |
| SCHEMBL3519711 | 0.73 | PGR (1.00) | AHRPGRPDE3BPDE3ACMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403554-A | Therapeutic or prophylactic agent for amyotrophic lateral sclerosis | 东丽株式会社 | 2025-02-07 | — | — | CN | disclosed |
| CN-116648245-A | Tetrahydroquinoline derivative and medical application thereof | 东丽株式会社 | 2023-08-25 | — | — | CN | disclosed |
| WO-2022138888-A1 | TETRAHYDROQUINOLINE DERIVATIVE AND MEDICINAL USE THEREOF | 東レ株式会社 | 2022-06-30 | — | — | WO | disclosed |