Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGMT | P16455 | 9/20 | 0.81 |
| ▸ | PIN1 | Q13526 | 9/20 | 0.78 |
| ▸ | CDK1 | P06493 | 9/20 | 0.78 |
| ▸ | CCNB1 | P14635 | 9/20 | 0.78 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.78 |
| ▸ | CDK2 | P24941 | 9/20 | 0.78 |
| ▸ | CCNA1 | P78396 | 9/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | BLM | P54132 | 1/20 | 0.78 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23124359 | 1.00 | MGMT (0.81) | MGMTPIN1CDK1CCNB1CCNA2 | |
| SCHEMBL3338895 | 0.88 | PIN1 (0.76) | MGMTPIN1CDK1CCNB1CCNA2 | |
| SCHEMBL3302852 | 0.88 | PIN1 (0.76) | MGMTPIN1CDK1CCNB1CCNA2 | |
| SCHEMBL3297931 | 0.88 | PIN1 (1.00) | MGMTPIN1CDK1CCNB1CCNA2 | |
| SCHEMBL3302326 | 0.88 | PIN1 (1.00) | MGMTPIN1CDK1CCNB1CCNA2 | |
| 6-O-Benzylguanine SCHEMBL61740 | 0.87 | PIN1 (1.00) | MGMTPIN1CDK1CCNB1CCNA2 | |
| 6-O-Benzylguanine SCHEMBL31517079 | 0.87 | PIN1 (1.00) | MGMTPIN1CDK1CCNB1CCNA2 | |
| 6-O-Benzylguanine SCHEMBL4631744 | 0.86 | PIN1 (0.97) | MGMTPIN1CDK1CCNB1CCNA2 | |
| SCHEMBL3305085 | 0.84 | PIN1 (0.75) | MGMTPIN1CDK1CCNB1CCNA2 | |
| SCHEMBL3305088 | 0.83 | PIN1 (0.73) | MGMTPIN1CDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146223-A | SNAP-tag probe and preparation and application thereof | 中国科学院大连化学物理研究所 | 2024-06-07 | — | — | CN | claimed |
| CN-119771379-A | 5-HTR2A cell membrane chromatographic solid phase microextraction material, preparation method thereof and application thereof in atypical antipsychotic TDM | 西安交通大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-119771380-A | Intracellular protein cell membrane stationary phase and chromatographic column based on SNAP-tag technology, preparation method thereof and application thereof in blood concentration monitoring | 西安交通大学 | 2025-04-08 | — | — | CN | disclosed |
| CN-118930573-A | Fluorescent dye sensitive to micro-environment viscosity and preparation method and application thereof | 上海交通大学 | 2024-11-12 | — | — | CN | disclosed |
| US-20240366799-A1 | CAGING-GROUP-FREE PHOTOACTIVATABLE FLUORESCENT DYES AND THEIR USE | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E. V. (DE) | 2024-11-07 | — | — | US | disclosed |
| CN-118339156-A | 2-Diazo-3-oxo-2, 3-dihydrospiro [ indene-1, 9' -xanthene ] derivatives and similar compounds as photoactive fluorescent compounds for protein labelling | 爱康治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118146223-A | SNAP-tag probe and preparation and application thereof | 中国科学院大连化学物理研究所 | 2024-06-07 | — | — | CN | disclosed |
| EP-4374157-A2 | FRET-BASED ASSAYS | The General Hospital Corporation (US) | 2024-05-29 | — | — | EP | disclosed |
| WO-2023004438-A2 | FRET-BASED ASSAYS | THE GENERAL HOSPITAL CORPORATION (US) | 2023-01-26 | — | — | WO | disclosed |
| EP-4031550-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | The University of Chicago (US) | 2022-07-27 | — | — | EP | disclosed |
| CN-114728970-A | Optical proximity analysis of protein-protein interactions in cells | 芝加哥大学 | 2022-07-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240366799-A1 | CAGING-GROUP-FREE PHOTOACTIVATABLE FLUORESCENT DYES AND THEIR USE | GNE, ALG1, PCNA | MGMT 1615/4885PIN1 1315/4885CDK1 393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.