SCHEMBL29749447

SCHEMBL29749447

O=C(O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CTRB1 P17538 1/20 0.48
▸ F2 P00734 2/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ MDM4 O15151 1/20 0.43
▸ TP53 P04637 1/20 0.43
▸ FDFT1 P37268 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ MAPK1 P28482 1/20 0.41
▸ TSHR P16473 2/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ MAPT P10636 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ RAB9A P51151 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ CASP3 P42574 1/20 0.41
▸ CTSK P43235 2/20 0.41
▸ CTSL P07711 1/20 0.41
▸ GFER P55789 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29777655 0.96 CTRB1 (0.46) CTRB1F2KMT2AMDM4TP53
SCHEMBL31501508 0.96 CTRB1 (0.46) CTRB1F2KMT2AMDM4TP53
SCHEMBL30688537 0.92 CTRB1 (0.44) CTRB1F2KMT2AFDFT1NPSR1
SCHEMBL29706288 0.91 CTRB1 (0.55) CTRB1F2KMT2AMDM4TP53
SCHEMBL29868206 0.90 CTRB1 (0.56) CTRB1F2KMT2AHSD17B10
SCHEMBL6434028 0.90 CTRB1 (0.56) CTRB1F2KMT2AHSD17B10
SCHEMBL29858987 0.89 CTRB1 (0.46) CTRB1F2KMT2AMDM4TP53
SCHEMBL29566581 0.89 CTRB1 (0.46) CTRB1F2KMT2AMDM4TP53
SCHEMBL29467321 0.88 F2 (0.45) F2KMT2AMDM4TP53FDFT1
SCHEMBL29750784 0.88 ACE (0.45) CTRB1F2FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039418-A Preparation method of Tirzepatide 江苏慧聚药业股份有限公司 2024-11-29 — — CN claimed
CN-114989313-B P-tau181 epitope peptide and application thereof in Alzheimer disease detection 福建亿彤生物科技有限公司 2024-04-02 — — CN claimed
CN-114989313-A P-tau181 epitope peptide and application thereof in Alzheimer disease detection 亿彤科技发展(福建)有限公司 2022-09-02 — — CN claimed
US-20250353875-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-11-20 — — US disclosed
EP-4509517-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-02-19 — — EP disclosed
CN-119431491-A Synthesis method of Fmoc-Xaa-Ser (Psi (Me, me) Pro) -OH pseudo dipeptide 杭州湃肽生化科技有限公司 2025-02-14 — — CN disclosed
CN-119039418-A Preparation method of Tirzepatide 江苏慧聚药业股份有限公司 2024-11-29 — — CN disclosed
CN-117866074-A Method for preparing teicoplanin by solid-liquid phase combination 瑞博(苏州)制药有限公司 2024-04-12 — — CN disclosed
CN-114989313-B P-tau181 epitope peptide and application thereof in Alzheimer disease detection 福建亿彤生物科技有限公司 2024-04-02 — — CN disclosed
US-20230391818-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-12-07 — — US disclosed
CN-117106093-A Double Fmoc-protected Tirzepatide backbone 39 peptide and synthesis method and application thereof 上海多米瑞生物技术有限公司 2023-11-24 — — CN disclosed
EP-4242219-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-09-13 — — EP disclosed
CN-116171164-A GLP-1/GIP dual agonists 太阳医药工业有限公司 2023-05-26 — — CN disclosed
CN-115768460-A Long-acting GLP-1/GIP dual agonists 太阳医药工业有限公司 2023-03-07 — — CN disclosed
CN-115181173-A Preparation method of Tirzepatide 深圳市健元医药科技有限公司 2022-10-14 — — CN disclosed
CN-114989313-A P-tau181 epitope peptide and application thereof in Alzheimer disease detection 亿彤科技发展(福建)有限公司 2022-09-02 — — CN disclosed
CN-114790236-A Synthetic method of GCGR/GLP-1R double-target-point agonist polypeptide 深圳市图微安创科技开发有限公司 2022-07-26 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230391818-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION VIP, DNPEP, NPPA CTRB1 2754/4885F2 3183/4885KMT2A 2159/4885
US-20250353875-A1 PEPTIDE SYNTHESIS METHOD FOR SUPPRESSING DEFECT CAUSED BY DIKETOPIPERAZINE FORMATION VIP, NPPA, DNPEP CTRB1 3178/4885F2 3694/4885KMT2A 2092/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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