Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 3/20 | 0.34 |
| ▸ | CASP7 | P55210 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 6/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098594 | 1.00 | PRNP (0.34) | PRNPRXFP1ALDH1A1KDM4ECASP1 | |
| SCHEMBL29750592 | 0.90 | NR1H2 (0.34) | ALDH1A1KDM4ENR1H2NR1H3KMT2A | |
| SCHEMBL24745629 | 0.86 | MEN1 (0.34) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL29750770 | 0.86 | MEN1 (0.34) | ALDH1A1KDM4EMAPTKMT2ALMNA | |
| SCHEMBL24597661 | 0.85 | ALDH1A1 (0.35) | PRNPRXFP1ALDH1A1KDM4ECASP1 | |
| SCHEMBL29750787 | 0.85 | MEN1 (0.36) | ALDH1A1KDM4EMAPTHSD17B10NR1H2 | |
| SCHEMBL29098616 | 0.84 | MAPT (0.35) | PRNPRXFP1ALDH1A1KDM4ECASP1 | |
| SCHEMBL29750607 | 0.84 | MAPT (0.35) | PRNPRXFP1ALDH1A1KDM4ECASP1 | |
| SCHEMBL29262066 | 0.78 | P2RY12 (0.33) | KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL29750494 | 0.78 | P2RY12 (0.33) | KDM4EKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271670-A1 | NOVEL COMPOUNDS WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | Captor Therapeutics S.A. (PL) | 2023-11-08 | — | — | EP | disclosed |
| CN-116917275-A | Novel CEREBLON-binding compounds and methods of use thereof | 凯普托尔治疗学股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| WO-2022144416-A1 | NOVEL COMPOUNDS WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2022-07-07 | — | — | WO | disclosed |