Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098616 | 1.00 | MAPT (0.35) | MAPTRXFP1KMT2AMEN1NPSR1 | |
| SCHEMBL29098613 | 0.90 | USP9X (0.37) | KMT2ANR1H2NR1H3 | |
| SCHEMBL29750591 | 0.90 | USP9X (0.37) | KMT2ANR1H2NR1H3 | |
| SCHEMBL24744948 | 0.86 | MAPT (0.35) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL29750507 | 0.86 | MAPT (0.35) | MAPTKMT2AMEN1NPSR1ALDH1A1 | |
| SCHEMBL24597664 | 0.85 | ALDH1A1 (0.36) | MAPTRXFP1KMT2AMEN1NPSR1 | |
| SCHEMBL29750567 | 0.85 | NMT2 (0.38) | MAPTRXFP1KMT2AMEN1NPSR1 | |
| SCHEMBL29098587 | 0.85 | NMT2 (0.38) | MAPTRXFP1KMT2AMEN1NPSR1 | |
| SCHEMBL29098594 | 0.84 | PRNP (0.34) | MAPTRXFP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL29750508 | 0.84 | PRNP (0.34) | MAPTRXFP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271670-A1 | NOVEL COMPOUNDS WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | Captor Therapeutics S.A. (PL) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022144416-A1 | NOVEL COMPOUNDS WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2022-07-07 | — | — | WO | disclosed |