Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29750770 | 0.90 | MEN1 (0.34) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL24745629 | 0.90 | MEN1 (0.34) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL29098597 | 0.85 | MAPT (0.36) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL29750575 | 0.85 | MAPT (0.36) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL29750507 | 0.84 | MAPT (0.35) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL24744948 | 0.84 | MAPT (0.35) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL29098598 | 0.76 | ALDH1A1 (0.38) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29750564 | 0.76 | ALDH1A1 (0.38) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29098594 | 0.76 | PRNP (0.34) | MAPTMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29750508 | 0.76 | PRNP (0.34) | MAPTMEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271670-A1 | NOVEL COMPOUNDS WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | Captor Therapeutics S.A. (PL) | 2023-11-08 | — | — | EP | disclosed |
| CN-116917275-A | Novel CEREBLON-binding compounds and methods of use thereof | 凯普托尔治疗学股份有限公司 | 2023-10-20 | — | — | CN | disclosed |
| WO-2022144416-A1 | NOVEL COMPOUNDS WHICH BIND TO CEREBLON, AND METHODS OF USE THEREOF | CAPTOR THERAPEUTICS S.A. (PL) | 2022-07-07 | — | — | WO | disclosed |