SCHEMBL29751128

SCHEMBL29751128

CC[C@H](C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21)C(C)C)C(C)C)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CASP3 P42574 3/20 0.47
▸ KMT2A Q03164 3/20 0.41
▸ CTSD P07339 1/20 0.40
▸ CTSB P07858 1/20 0.38
▸ CTSK P43235 1/20 0.38
▸ TLR2 O60603 1/20 0.38
▸ CXCR2 P25025 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29750824 0.98 CASP3 (0.48) CASP3KMT2ACTSDCTSBCTSK
SCHEMBL29750816 0.95 CASP3 (0.49) CASP3KMT2ACTSDCTSBCTSK
SCHEMBL30560164 0.92 CASP3 (0.53) CASP3KMT2ATLR2
SCHEMBL29750940 0.89 CASP3 (0.57) CASP3KMT2ACTSBCTSKMEN1
SCHEMBL29750832 0.89 CASP3 (0.57) CASP3KMT2ACTSBCTSKMEN1
SCHEMBL31321058 0.88 CASP3 (0.43) CASP3KMT2ACTSBCTSKTLR2
SCHEMBL29750819 0.87 CASP3 (0.42) CASP3CTSBCTSKTLR2
SCHEMBL29750822 0.85 CASP3 (0.53) CASP3KMT2ACTSBMEN1LMNA
SCHEMBL30143372 0.85 KMT2A (0.47) CASP3KMT2ACTSBTLR2MEN1
SCHEMBL29603695 0.83 KMT2A (0.51) CASP3KMT2ATLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114920851-B Aβ1-42 antigen and use thereof for detecting Aβ1-42 concentration in Alzheimer's patient 福建亿彤生物科技有限公司 2024-05-31 — — CN claimed
CN-114957438-B Human Abeta 1-42 epitope polypeptide for detecting Alzheimer disease and preparation method thereof 福建亿彤生物科技有限公司 2024-04-02 — — CN claimed
CN-114957438-A Human Abeta 1-42 antigenic determinant polypeptide for detecting Alzheimer disease and preparation method thereof 亿彤科技发展(福建)有限公司 2022-08-30 — — CN claimed
CN-114920851-B Aβ1-42 antigen and use thereof for detecting Aβ1-42 concentration in Alzheimer's patient 福建亿彤生物科技有限公司 2024-05-31 — — CN disclosed
CN-114957438-B Human Abeta 1-42 epitope polypeptide for detecting Alzheimer disease and preparation method thereof 福建亿彤生物科技有限公司 2024-04-02 — — CN disclosed
CN-114957438-A Human Abeta 1-42 antigenic determinant polypeptide for detecting Alzheimer disease and preparation method thereof 亿彤科技发展(福建)有限公司 2022-08-30 — — CN disclosed
CN-114920851-A Abeta 1-42 antigen and application thereof in detecting Abeta 1-42 concentration in Alzheimer patient 亿彤科技发展(福建)有限公司 2022-08-19 — — CN disclosed
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