Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29750824 | 0.94 | CASP3 (0.48) | CASP3KMT2ATLR2 | |
| SCHEMBL29751128 | 0.92 | CASP3 (0.47) | CASP3KMT2ATLR2 | |
| SCHEMBL30560165 | 0.91 | CASP3 (0.53) | CASP3KMT2A | |
| SCHEMBL8902890 | 0.91 | KMT2A (0.51) | CASP3KMT2AMDM4TP53TLR2 | |
| SCHEMBL29697708 | 0.91 | KMT2A (0.51) | CASP3KMT2AMDM4TP53TLR2 | |
| SCHEMBL27637562 | 0.91 | KMT2A (0.51) | CASP3KMT2AMDM4TP53TLR2 | |
| SCHEMBL29603695 | 0.91 | KMT2A (0.51) | CASP3KMT2AMDM4TP53TLR2 | |
| SCHEMBL18429471 | 0.90 | KMT2A (0.53) | CASP3KMT2AMDM4TP53TLR2 | |
| SCHEMBL30028151 | 0.90 | KMT2A (0.53) | CASP3KMT2AMDM4TP53TLR2 | |
| SCHEMBL1668211 | 0.90 | KMT2A (0.53) | CASP3KMT2AMDM4TP53TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4643883-A2 | ANTIBODY-DRUG CONJUGATE CONTAINING N-METHYLENE AMIDE LINKER | Hangzhou Adcoris Biopharma Co., Ltd (CN) | 2025-11-05 | — | — | EP | disclosed |
| CN-116712563-A | Antibody conjugated drugs of N-haloalkyl substituted camptothecin derivatives | 杭州爱科瑞思生物医药有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116712561-A | Antibody-drug conjugates containing an N-methyleneamide linker | 杭州爱科瑞思生物医药有限公司 | 2023-09-08 | — | — | CN | disclosed |