Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 16/20 | 0.70 |
| ▸ | WNT1 | P04628 | 14/20 | 0.70 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.59 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810251 | 1.00 | DYRK1A (0.70) | DYRK1AWNT1NR4A2HTR4KDM1A | |
| SCHEMBL17095536 | 0.82 | DYRK1A (1.00) | DYRK1AWNT1 | |
| SCHEMBL31123870 | 0.82 | DYRK1A (1.00) | DYRK1AWNT1 | |
| SCHEMBL29754034 | 0.82 | HTR4 (0.59) | DYRK1AWNT1HTR4KDM1A | |
| SCHEMBL28809209 | 0.82 | HTR4 (0.59) | DYRK1AWNT1HTR4KDM1A | |
| SCHEMBL23533891 | 0.81 | HTR4 (0.56) | DYRK1AWNT1HTR4KDM1A | |
| SCHEMBL29753901 | 0.81 | HTR4 (0.56) | DYRK1AWNT1HTR4KDM1A | |
| SCHEMBL15615178 | 0.80 | DYRK1A (0.65) | DYRK1AWNT1 | |
| SCHEMBL28809778 | 0.78 | HTR4 (0.60) | DYRK1AWNT1HTR4KDM1A | |
| SCHEMBL29753960 | 0.78 | HTR4 (0.60) | DYRK1AWNT1HTR4KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |