Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL193884 | 1.00 | PTGS2 (0.36) | PTGS2NAMPTALDH3A1PTGS1TP53 | |
| Hydrochloric Acid SCHEMBL1278763 | 0.99 | PTGS2 (0.35) | PTGS2NAMPTALDH3A1PTGS1TP53 | |
| SCHEMBL1278078 | 0.89 | NAMPT (0.33) | PTGS2NAMPTHTR6EEDL3MBTL1 | |
| Vonoprazan SCHEMBL29419683 | 0.87 | GAA (0.40) | NAMPTGAAKMT2AHTR6CYP11B1 | |
| Vonoprazan SCHEMBL194487 | 0.87 | GAA (0.40) | NAMPTGAAKMT2AHTR6CYP11B1 | |
| Vonoprazan SCHEMBL29407860 | 0.87 | GAA (0.40) | NAMPTGAAKMT2AHTR6CYP11B1 | |
| Vonoprazan SCHEMBL29419681 | 0.87 | GAA (0.40) | NAMPTGAAKMT2AHTR6CYP11B1 | |
| Vonoprazan SCHEMBL29559657 | 0.86 | GAA (0.39) | NAMPTGAAKMT2AHTR6CYP11B1 | |
| Vonoprazan SCHEMBL28725455 | 0.86 | GAA (0.39) | NAMPTGAAKMT2AHTR6CYP11B1 | |
| SCHEMBL1762729 | 0.85 | NAMPT (0.38) | PTGS2NAMPTALDH3A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110200903-B | Liquid formulations of amines and organic acids stabilized with salts | 武田药品工业株式会社 | 2022-07-29 | — | — | CN | claimed |
| CN-113149883-B | Process for preparing pyrrole compounds | 武田药品工业株式会社 | 2024-04-02 | — | — | CN | disclosed |
| CN-114835619-A | Process for preparing azole compounds | 武田药品工业株式会社 | 2022-08-02 | — | — | CN | disclosed |
| CN-110200903-B | Liquid formulations of amines and organic acids stabilized with salts | 武田药品工业株式会社 | 2022-07-29 | — | — | CN | disclosed |