Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2497788 | 1.00 | CRBN (0.64) | CRBNALDH1A1LMNASMYD3ALOX15 | |
| SCHEMBL17276396 | 0.91 | LMNA (0.56) | CRBNALDH1A1LMNASMYD3ALOX15 | |
| SCHEMBL6646602 | 0.88 | CRBN (0.76) | CRBNALDH1A1LMNASMYD3ALOX15 | |
| SCHEMBL1359221 | 0.86 | CRBN (0.59) | CRBNALDH1A1LMNASMYD3HTT | |
| SCHEMBL29374811 | 0.86 | CRBN (0.59) | CRBNALDH1A1LMNASMYD3HTT | |
| SCHEMBL3066386 | 0.84 | SMYD3 (0.48) | CRBNALDH1A1SMYD3ALOX15HSD17B10 | |
| SCHEMBL2218590 | 0.83 | CA9 (0.56) | CRBNSMYD3ALOX15CA9NPC1 | |
| SCHEMBL17957924 | 0.82 | ALDH1A1 (0.56) | CRBNALDH1A1LMNAALOX15HSD17B10 | |
| Acetic Acid SCHEMBL30195764 | 0.82 | CRBN (0.56) | CRBNALDH1A1LMNASMYD3HTT | |
| Phosphoric Acid SCHEMBL30195978 | 0.81 | CRBN (0.58) | CRBNALDH1A1LMNASMYD3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436955-B | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-114436955-A | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2022-05-06 | — | — | CN | disclosed |