Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720579 | 1.00 | GAA (0.42) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9211517 | 1.00 | GAA (0.42) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9562462 | 1.00 | GAA (0.42) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL5256942 | 0.94 | GAA (0.48) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9492350 | 0.94 | GAA (0.48) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL10592860 | 0.94 | GAA (0.48) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL29445577 | 0.90 | HPGD (0.43) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9489704 | 0.90 | HPGD (0.43) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9874727 | 0.90 | HPGD (0.43) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9627791 | 0.88 | MAPT (0.36) | GAAHPGDMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436875-B | Preparation method of cyclopropylethyl amide | 江苏飞宇医药科技股份有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-114436875-A | Preparation method of cyclopropylethyl amide | 江苏飞宇医药科技股份有限公司 | 2022-05-06 | — | — | CN | disclosed |