Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9720579 | 1.00 | GAA (0.42) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL29754269 | 1.00 | GAA (0.42) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9562462 | 1.00 | GAA (0.42) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL5256942 | 0.94 | GAA (0.48) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9492350 | 0.94 | GAA (0.48) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL10592860 | 0.94 | GAA (0.48) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL29445577 | 0.90 | HPGD (0.43) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9489704 | 0.90 | HPGD (0.43) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9874727 | 0.90 | HPGD (0.43) | GAAHPGDMAPTNPC1RAB9A | |
| SCHEMBL9627791 | 0.88 | MAPT (0.36) | GAAHPGDMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436875-B | Preparation method of cyclopropylethyl amide | 江苏飞宇医药科技股份有限公司 | 2023-05-12 | — | — | CN | disclosed |
| CN-114436875-A | Preparation method of cyclopropylethyl amide | 江苏飞宇医药科技股份有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-0457090-B1 | Process for the preparation of 3-amino-2 (het)aroyl-acrylic acid derivatives | BAYER AG (DE) | 1995-11-29 | — | — | EP | disclosed |
| US-5182401-A | Bactericide intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1993-01-26 | — | — | US | disclosed |
| US-5169853-A | Antibacterial agents; administering to mammals for infection | STERLING DRUG INC. (US) | 1992-12-08 | — | — | US | disclosed |
| US-5077429-A | 7-AMINO-1-CYCLOPROPYL-4-OXO-1,4-DIHYDRO-QUINOLINE- AND NAPHTHYRIDINE-3-CARBOXYLIC ACIDS, PROCESSES FOR THEIR PREPARATION AND ANTIBACTERIAL AGENTS CONTAINING THESE COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-12-31 | — | — | US | disclosed |
| US-5075319-A | Bactericides | STERLING DRUG INC. (US) | 1991-12-24 | — | — | US | disclosed |
| EP-0457090-A2 | Process for the preparation of 3-amino-2 (het)aroyl-acrylic acid derivatives | BAYER AG (DE) | 1991-11-21 | — | — | EP | disclosed |
| EP-0176846-B1 | 3-AMINO-2-BENZOYL-ACRYLIC-ACID DERIVATIVES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1989-08-16 | — | — | EP | disclosed |
| US-4699992-A | 3-amino-2-benzoylacrylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-13 | — | — | US | disclosed |
| US-4559341-A | Quinolonecarboxylic acids and antibacterial agents containing these compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1985-12-17 | — | — | US | disclosed |
| US-4547503-A | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-(oxo-alkyl)-1-piperazinyl]quinoline-3-carboxylic acids and their derivatives, and antibacterial agents containing them | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-15 | — | — | US | disclosed |
| US-4544658-A | FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |
| EP-0121727-A1 | Bactericidal agent based on quinolonecarboxylic acids | BAYER AG (DE) | 1984-10-17 | — | — | EP | disclosed |
| EP-0118854-A1 | Bactericidal agent containing quinolone-carboxylic acids | BAYER AG (DE) | 1984-09-19 | — | — | EP | disclosed |
| EP-0117473-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0117474-A1 | Quinolone carboxylic acids, process for their preparation and antibacterial compositions containing them | BAYER AG (DE) | 1984-09-05 | — | — | EP | disclosed |
| EP-0113093-A1 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(alkyl-1-piperazinyl)-3-quinoline-carboxylic acids, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |
| EP-0113091-A1 | Microbiocidal agents based on quinolone-carboxylic acids | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |
| EP-0113092-A1 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(oxoalkyl)-1-piperazinyl)-3-quinoline-carboxylic acids and their derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |