Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 15/20 | 0.51 |
| ▸ | MAOA | P21397 | 13/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28778408 | 1.00 | CA9 (0.53) | CA9MAOBMAOADRD2ADRA1D | |
| SCHEMBL29754348 | 0.84 | CA9 (0.54) | CA9MAOBMAOADRD2ADRA1D | |
| SCHEMBL28778391 | 0.84 | CA9 (0.54) | CA9MAOBMAOADRD2ADRA1D | |
| SCHEMBL4184334 | 0.82 | CA9 (0.51) | CA9MAOBMAOADRD2ADRA1D | |
| SCHEMBL29594795 | 0.82 | CA9 (0.51) | CA9MAOBMAOADRD2ADRA1D | |
| SCHEMBL4196140 | 0.76 | DRD2 (0.50) | CA9MAOBMAOADRD2ADRA1D | |
| SCHEMBL703728 | 0.75 | MAOB (0.58) | CA9MAOBMAOAAOC3EIF2AK2 | |
| SCHEMBL29724095 | 0.75 | MAOB (0.58) | CA9MAOBMAOAAOC3EIF2AK2 | |
| SCHEMBL8109567 | 0.75 | CA9 (0.62) | CA9MAOBMAOAAOC3EIF2AK2 | |
| SCHEMBL18850317 | 0.75 | MAOB (0.58) | CA9MAOBMAOAAOC3EIF2AK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436955-B | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2024-08-09 | — | — | CN | disclosed |
| CN-114436955-A | Tetrahydroquinoline and benzomorpholine derivatives or salts thereof, and preparation method and application thereof | 复旦大学 | 2022-05-06 | — | — | CN | disclosed |