Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | EGFR | P00533 | 3/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.80 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 10/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.76 |
| ▸ | TSHR | P16473 | 6/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.76 |
| ▸ | USP2 | O75604 | 4/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083926 | 1.00 | MAPT (1.00) | MAPTEGFRNPSR1PKMMEN1 | |
| SCHEMBL1084041 | 0.89 | KMT2A (1.00) | MAPTEGFRNPSR1PKMMEN1 | |
| SCHEMBL28618804 | 0.87 | MAPT (0.77) | MAPTEGFRNPSR1PKMMEN1 | |
| SCHEMBL1064854 | 0.84 | CYP1A2 (1.00) | MAPTEGFRNPSR1PKMMEN1 | |
| SCHEMBL7277274 | 0.83 | CYP1A2 (1.00) | MAPTNPSR1MEN1KMT2ACYP1A2 | |
| SCHEMBL7286130 | 0.79 | PDE5A (1.00) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL14262933 | 0.79 | CYP1A2 (0.84) | MAPTEGFRNPSR1PKMMEN1 | |
| SCHEMBL4511106 | 0.77 | MAPT (0.62) | MAPTEGFRNPSR1PKMMEN1 | |
| SCHEMBL1083858 | 0.76 | MEN1 (0.71) | MAPTEGFRNPSR1PKMMEN1 | |
| SCHEMBL28604939 | 0.76 | CYP1A2 (0.78) | MAPTEGFRNPSR1PKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113880859-B | 2-aryl-4-arylmethylamino pyrimidine compound and application thereof | 江西科技师范大学 | 2022-06-21 | — | — | CN | disclosed |