SCHEMBL29754646

SCHEMBL29754646

CSCC[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CS)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 7/20 0.53
▸ CTSL P07711 3/20 0.53
▸ CTSS P25774 3/20 0.53
▸ CTSK P43235 3/20 0.53
▸ CTSH P09668 1/20 0.53
▸ GLP1R P43220 5/20 0.53
▸ GCGR P47871 2/20 0.53
▸ GIPR P48546 1/20 0.53
▸ GRPR P30550 2/20 0.52
▸ TUBB4A P04350 1/20 0.51
▸ TUBB P07437 1/20 0.51
▸ TUBA3C P0DPH7 1/20 0.51
▸ TUBA1B P68363 1/20 0.51
▸ TUBA4A P68366 1/20 0.51
▸ TUBB4B P68371 1/20 0.51
▸ TUBB3 Q13509 1/20 0.51
▸ TUBB2A Q13885 1/20 0.51
▸ TUBB8 Q3ZCM7 1/20 0.51
▸ TUBA3E Q6PEY2 1/20 0.51
▸ TUBA1A Q71U36 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30859279 0.89 GLP1R (0.64) GLP1RGCGRGIPR
SCHEMBL29613381 0.88 GLP1R (0.61) IL23RGLP1RGCGR
SCHEMBL30878115 0.88 GHSR (0.57) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29883587 0.87 IL23R (0.61) IL23RGLP1RGCGRTUBB4ATUBB
SCHEMBL29540806 0.87 IL23R (0.60) IL23RGLP1RGCGRTUBB4ATUBB
SCHEMBL30264983 0.87 C5AR1 (0.51) IL23RCTSLCTSSCTSKCTSH
SCHEMBL30264893 0.87 C5AR1 (0.51) IL23RCTSLCTSSCTSKCTSH
SCHEMBL30264997 0.87 C5AR1 (0.51) IL23RCTSLCTSSCTSKCTSH
SCHEMBL31688318 0.87 IL23R (0.64) IL23RGLP1RGCGRGIPR
SCHEMBL31140223 0.87 TUBB4A (0.56) IL23RGLP1RTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111094324-B Oncolytic virus, synthetic DNA sequence and application thereof 武汉博威德生物技术有限公司 2023-10-10 — — CN claimed
US-20220288142-A1 RECOMBINANT ONCOLYTIC VIRUS, SYNTHETIC DNA SEQUENCE, AND APPLICATION THEREOF Wuhan Boweid Biotechnology Co., Ltd. (CN) 2022-09-15 — — US claimed
CN-111094324-B Oncolytic virus, synthetic DNA sequence and application thereof 武汉博威德生物技术有限公司 2023-10-10 — — CN disclosed
US-20220288142-A1 RECOMBINANT ONCOLYTIC VIRUS, SYNTHETIC DNA SEQUENCE, AND APPLICATION THEREOF Wuhan Boweid Biotechnology Co., Ltd. (CN) 2022-09-15 — — US disclosed
US-11376290-B2 Recombinant oncolytic virus, synthetic DNA sequence, and application thereof Wuhan Boweid Biotechnology Co., Ltd. (CN) 2022-07-05 — — US disclosed
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