Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29756406 | 0.84 | PTPN5 (0.52) | KDM4ERAB9AALDH1A1NPC1HPGD | |
| SCHEMBL29756454 | 0.84 | DYRK1A (0.45) | KDM4ERAB9AALDH1A1NPC1HPGD | |
| SCHEMBL29756387 | 0.83 | CHEK2 (0.50) | RAB9ANPC1DYRK1AMEN1KMT2A | |
| SCHEMBL21219204 | 0.74 | KDM4E (0.51) | KDM4ERAB9AALDH1A1NPC1HPGD | |
| Glycozoline SCHEMBL11981403 | 0.72 | ALDH1A1 (0.81) | KDM4ERAB9AALDH1A1NPC1HPGD | |
| SCHEMBL6123447 | 0.72 | MAOA (0.68) | KDM4EALDH1A1HPGDSMN1; SMN2DYRK1A | |
| SCHEMBL677993 | 0.71 | EGFR (0.47) | KDM4ERAB9AALDH1A1NPC1HPGD | |
| SCHEMBL27255881 | 0.71 | KDM4E (0.59) | KDM4ERAB9AALDH1A1NPC1HPGD | |
| SCHEMBL1921071 | 0.70 | KDM4E (0.47) | KDM4ERAB9AALDH1A1NPC1HPGD | |
| SCHEMBL22719994 | 0.69 | BCHE (0.40) | KDM4ERAB9AALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110382496-B | Substituted pyrido [3,4-b ] indoles for the treatment of cartilage disorders | 赛诺菲 | 2022-08-09 | — | — | CN | disclosed |