SCHEMBL2975748

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2977504	0.80	PPARG (0.45)	ELANEPTGER4PPARGPPARACYP2C9
	SCHEMBL2984630	0.78	GCGR (0.39)	PTGER4KCNH2HPGDGCGR
	SCHEMBL2972036	0.78	PPARG (0.40)	ELANEPTGER4PPARGPPARACYP2C9
	SCHEMBL2972040	0.78	PPARG (0.40)	ELANEPTGER4PPARGPPARACYP2C9
	SCHEMBL14409114	0.77	ELANE (0.38)	ELANEPTGER4PPARGPPARACYP2C9
	SCHEMBL2986233	0.70	PTGER4 (0.42)	ELANEPTGER4
	SCHEMBL10074210	0.70	ALDH1A1 (0.43)	ELANEPTGER4SLC6A2SLC6A3TP53
	SCHEMBL13078121	0.67	SMN1; SMN2 (0.42)	TP53MAPTSMN1; SMN2KMT2A
	SCHEMBL2969551	0.66	KDM4E (0.54)	TP53MAPTSMN1; SMN2KMT2AAKR1C3
	SCHEMBL2977493	0.65	MEN1 (0.51)	CYP2C9GAAHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.