Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | HTT | P42858 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23466602 | 1.00 | SMN1; SMN2 (0.67) | SMN1; SMN2L3MBTL1HPGDKDM4EGAA | |
| SCHEMBL419126 | 0.83 | L3MBTL1 (0.51) | SMN1; SMN2L3MBTL1HPGDKDM4EGAA | |
| SCHEMBL10625637 | 0.81 | MAPK1 (0.57) | SMN1; SMN2L3MBTL1HPGDKDM4EGAA | |
| SCHEMBL677962 | 0.80 | KDM4E (1.00) | SMN1; SMN2L3MBTL1HPGDKDM4EGAA | |
| SCHEMBL29805501 | 0.79 | KDM4E (0.60) | SMN1; SMN2L3MBTL1HPGDKDM4EGAA | |
| SCHEMBL2193401 | 0.79 | KMT2A (0.47) | SMN1; SMN2L3MBTL1HPGDKDM4EGAA | |
| SCHEMBL10623794 | 0.78 | MAPK1 (0.60) | SMN1; SMN2L3MBTL1HPGDKDM4EGAA | |
| SCHEMBL29758112 | 0.77 | KMT2A (0.63) | SMN1; SMN2L3MBTL1HPGDKDM4EGAA | |
| SCHEMBL23486528 | 0.77 | ALDH1A1 (1.00) | SMN1; SMN2L3MBTL1KDM4EGAACYP1A2 | |
| SCHEMBL560040 | 0.77 | KMT2A (0.63) | SMN1; SMN2L3MBTL1HPGDKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |