Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | HTR2B | P41595 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.46 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486753 | 1.00 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL9066974 | 0.83 | KDM4E (0.51) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL1136235 | 0.82 | HTR2A (0.51) | NPC1RAB9AKMT2AHTR2CHTR2B | |
| SCHEMBL19174691 | 0.82 | SIGMAR1 (0.40) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL19175208 | 0.80 | KMT2A (0.52) | KMT2ALMNAVCAM1SLC6A4MAPK1 | |
| SCHEMBL28592235 | 0.80 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2KMT2ALMNAVCAM1 | |
| SCHEMBL10387432 | 0.79 | PDE7A (0.71) | ALDH1A1SMN1; SMN2KMT2AKDM4EPDE7A | |
| SCHEMBL3803035 | 0.78 | NPC1 (0.64) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL19175417 | 0.78 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL17395846 | 0.78 | POLB (0.54) | ALDH1A1SMN1; SMN2KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |