Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 3/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | DRD5 | P21918 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.49 |
| ▸ | RET | P07949 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2981971 | 0.86 | HRH3 (0.65) | HRH1HRH3 | |
| SCHEMBL2981464 | 0.84 | LTA4H (0.55) | HRH1HTR2AHRH3 | |
| SCHEMBL2975455 | 0.83 | FLT1 (0.57) | HRH1HRH3 | |
| SCHEMBL2975828 | 0.83 | SLC6A2 (0.58) | SLC6A2SLC6A4DRD2DRD3DRD1 | |
| SCHEMBL2984893 | 0.78 | HRH3 (0.62) | HRH1HRH3 | |
| SCHEMBL2990306 | 0.77 | PRKCQ (0.57) | HRH1HRH3 | |
| SCHEMBL29785720 | 0.77 | SLC6A2 (0.57) | SLC6A2SLC6A4DRD2DRD3DRD1 | |
| SCHEMBL2984516 | 0.76 | HRH3 (0.64) | HRH1HTR2AHRH3RET | |
| SCHEMBL29785717 | 0.76 | SLC6A2 (0.66) | SLC6A2SLC6A4DRD2DRD3DRD1 | |
| SCHEMBL28810713 | 0.76 | SLC6A2 (0.66) | SLC6A2SLC6A4DRD2DRD3DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781591-B2 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC (US) | 2010-08-24 | — | — | US | disclosed |
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | WYETH LLC | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287708-A1 | Substituted 3-cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K7 | SLC6A2 4329/4885SLC6A4 4388/4885DRD2 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.