Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 12/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 2/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6120877 | 0.76 | ACE (0.49) | ACEOXTRAVPR1A | |
| SCHEMBL6972439 | 0.75 | RORC (0.34) | NAMPTRIPK1RORCGRM5 | |
| SCHEMBL19960681 | 0.72 | F11 (0.55) | ACE | |
| SCHEMBL29758654 | 0.70 | HSP90AA1 (0.46) | ACEOXTRAVPR1A | |
| SCHEMBL18986869 | 0.70 | RORC (0.48) | RORCACE | |
| SCHEMBL4553795 | 0.69 | NAMPT (0.44) | NAMPTRIPK1GRM5 | |
| SCHEMBL6251794 | 0.68 | MEN1 (0.44) | NAMPTACEOXTRAVPR1A | |
| SCHEMBL29897757 | 0.66 | ACE (0.54) | ACE | |
| SCHEMBL28841911 | 0.66 | ACE (0.54) | ACE | |
| SCHEMBL28841912 | 0.66 | ACE (0.54) | ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390396-B1 | ISOINDOLE COMPOUNDS | ASTRAZENECA AB (SE) | 2022-07-06 | — | — | EP | disclosed |